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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGF5 All Species: 7.27
Human Site: S258 Identified Species: 20
UniProt: P12034 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12034 NP_004455.2 268 29551 S258 A P R K N T N S V K Y R L K F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089996 268 29617 T258 A P R K N T N T V K Y R L K F
Dog Lupus familis XP_848478 207 22962 R198 L P R P G I Q R E F L N V Q R
Cat Felis silvestris
Mouse Mus musculus P15656 264 29085 P254 Q P R R S P S P V K Y R L K F
Rat Rattus norvegicus P48807 266 29246 P256 P S R R S P S P V K Y R L K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505458 172 19227 V163 P R K S S T T V K Y K L K F R
Chicken Gallus gallus P48801 220 25031 S211 E S L L K P P S K N Q R R R R
Frog Xenopus laevis Q91875 209 23644 E200 V D P E K V P E L Y K D I L S
Zebra Danio Brachydanio rerio P48802 256 28905 S247 R R R R H R G S K G H N R R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.7 30.9 N.A. 84.3 83.5 N.A. 55.2 28.7 32 34.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 99.2 45.5 N.A. 89.1 88.4 N.A. 59.7 43.6 44.7 50 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 13.3 N.A. 60 53.3 N.A. 6.6 13.3 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 26.6 N.A. 80 73.3 N.A. 20 20 20 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 0 0 0 0 0 0 0 12 0 0 0 % D
% Glu: 12 0 0 12 0 0 0 12 12 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 12 0 0 0 12 45 % F
% Gly: 0 0 0 0 12 0 12 0 0 12 0 0 0 0 0 % G
% His: 0 0 0 0 12 0 0 0 0 0 12 0 0 0 0 % H
% Ile: 0 0 0 0 0 12 0 0 0 0 0 0 12 0 0 % I
% Lys: 0 0 12 23 23 0 0 0 34 45 23 0 12 45 0 % K
% Leu: 12 0 12 12 0 0 0 0 12 0 12 12 45 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 23 0 23 0 0 12 0 23 0 0 0 % N
% Pro: 23 45 12 12 0 34 23 23 0 0 0 0 0 0 0 % P
% Gln: 12 0 0 0 0 0 12 0 0 0 12 0 0 12 0 % Q
% Arg: 12 23 67 34 0 12 0 12 0 0 0 56 23 23 34 % R
% Ser: 0 23 0 12 34 0 23 34 0 0 0 0 0 0 12 % S
% Thr: 0 0 0 0 0 34 12 12 0 0 0 0 0 0 0 % T
% Val: 12 0 0 0 0 12 0 12 45 0 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 23 45 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _