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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KRT3 All Species: 2.42
Human Site: S556 Identified Species: 7.62
UniProt: P12035 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12035 NP_476429.2 629 64504 S556 G G L G G G F S A G G G S G S
Chimpanzee Pan troglodytes A5A6M8 592 62520 G505 S S V S S G Y G S G S G Y G G
Rhesus Macaque Macaca mulatta XP_001097493 633 65708 G539 S G G Y R G G G S S S G Y G V
Dog Lupus familis XP_543641 535 57544 S466 G E C P S A V S I S V T G N S
Cat Felis silvestris
Mouse Mus musculus Q3UV17 594 62826 G523 D S S G R S G G S S S S S S R
Rat Rattus norvegicus Q6P6Q2 576 61807 G499 N S L S S G Y G G R S N I G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505912 616 63164 G540 F G R G G G F G S G G G F G S
Chicken Gallus gallus O93532 492 53785 S423 K L L E G E E S R L A G D G V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.7 77.2 57 N.A. 70.2 63.1 N.A. 77.9 53.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73.2 84.3 67.8 N.A. 78.2 73.1 N.A. 85.8 64.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 26.6 20 N.A. 13.3 20 N.A. 66.6 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 46.6 33.3 20 N.A. 20 26.6 N.A. 73.3 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 13 0 0 13 0 13 0 0 0 0 % A
% Cys: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % D
% Glu: 0 13 0 13 0 13 13 0 0 0 0 0 0 0 0 % E
% Phe: 13 0 0 0 0 0 25 0 0 0 0 0 13 0 0 % F
% Gly: 25 38 13 38 38 63 25 63 13 38 25 63 13 75 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 13 0 0 0 13 0 0 % I
% Lys: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 13 38 0 0 0 0 0 0 13 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 0 0 0 0 0 0 0 0 0 0 13 0 13 0 % N
% Pro: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 13 0 25 0 0 0 13 13 0 0 0 0 13 % R
% Ser: 25 38 13 25 38 13 0 38 50 38 50 13 25 13 38 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % T
% Val: 0 0 13 0 0 0 13 0 0 0 13 0 0 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 13 0 0 25 0 0 0 0 0 25 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _