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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX6A1
All Species:
12.73
Human Site:
S16
Identified Species:
23.33
UniProt:
P12074
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12074
NP_004364.2
109
12155
S16
V
S
R
L
L
G
R
S
R
P
Q
L
G
R
P
Chimpanzee
Pan troglodytes
XP_518442
109
12123
S16
V
S
R
L
L
G
R
S
R
P
Q
L
G
R
P
Rhesus Macaque
Macaca mulatta
XP_001088806
109
12047
S16
V
S
R
L
L
G
R
S
G
P
Q
L
G
R
P
Dog
Lupus familis
XP_534704
110
11991
S17
L
S
G
L
L
G
R
S
G
A
P
L
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
P43024
111
12334
A18
V
S
R
P
L
G
R
A
L
P
G
L
R
R
P
Rat
Rattus norvegicus
P10818
111
12283
A18
V
S
G
L
L
G
R
A
L
P
R
V
G
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510407
75
8765
Chicken
Gallus gallus
XP_415270
108
11797
G16
R
L
L
P
A
A
P
G
S
V
P
A
R
S
M
Frog
Xenopus laevis
NP_001091288
105
11966
F13
A
R
M
S
S
L
I
F
R
R
E
M
A
S
E
Zebra Danio
Brachydanio rerio
NP_001005592
108
12193
A16
Q
K
L
F
K
S
A
A
L
T
Q
S
R
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20779
128
14724
V30
S
F
Y
G
S
N
N
V
E
G
F
K
E
S
Y
Sea Urchin
Strong. purpuratus
XP_001192461
115
12958
T22
T
S
L
T
R
R
S
T
A
T
A
H
G
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32799
129
15003
A29
F
G
P
P
D
K
V
A
A
Q
K
F
K
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
93.5
83.6
N.A.
82.8
81.9
N.A.
56.8
65.1
55
62.3
N.A.
N.A.
N.A.
31.2
45.2
Protein Similarity:
100
98.1
94.5
87.2
N.A.
87.3
90
N.A.
59.6
74.3
66.9
72.4
N.A.
N.A.
N.A.
46.8
55.6
P-Site Identity:
100
100
93.3
60
N.A.
66.6
66.6
N.A.
0
0
6.6
6.6
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
93.3
66.6
N.A.
73.3
86.6
N.A.
0
0
20
20
N.A.
N.A.
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
8
31
16
8
8
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
8
0
8
8
8
% E
% Phe:
8
8
0
8
0
0
0
8
0
0
8
8
0
0
0
% F
% Gly:
0
8
16
8
0
47
0
8
16
8
8
0
47
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
8
0
0
0
0
8
8
8
0
0
% K
% Leu:
8
8
24
39
47
8
0
0
24
0
0
39
0
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
24
0
0
8
0
0
39
16
0
0
8
39
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
31
0
0
8
0
% Q
% Arg:
8
8
31
0
8
8
47
0
24
8
8
0
24
47
0
% R
% Ser:
8
54
0
8
16
8
8
31
8
0
0
8
0
24
16
% S
% Thr:
8
0
0
8
0
0
0
8
0
16
0
0
0
0
0
% T
% Val:
39
0
0
0
0
0
8
8
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _