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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX6A1
All Species:
10.91
Human Site:
Y58
Identified Species:
20
UniProt:
P12074
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12074
NP_004364.2
109
12155
Y58
A
V
S
M
L
N
V
Y
L
K
S
H
H
G
E
Chimpanzee
Pan troglodytes
XP_518442
109
12123
Y58
A
V
S
M
L
N
V
Y
L
K
S
H
H
G
E
Rhesus Macaque
Macaca mulatta
XP_001088806
109
12047
Y58
A
V
S
M
L
N
V
Y
L
K
S
H
H
G
E
Dog
Lupus familis
XP_534704
110
11991
F59
G
V
S
M
L
N
V
F
L
K
S
H
H
G
E
Cat
Felis silvestris
Mouse
Mus musculus
P43024
111
12334
F60
G
V
S
M
L
N
V
F
L
K
S
R
H
E
E
Rat
Rattus norvegicus
P10818
111
12283
F60
G
V
S
M
L
N
V
F
L
K
S
R
H
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510407
75
8765
K25
S
M
L
N
A
Y
L
K
E
Q
Q
H
S
G
H
Chicken
Gallus gallus
XP_415270
108
11797
L58
V
C
M
L
N
C
Y
L
K
A
Q
H
E
H
E
Frog
Xenopus laevis
NP_001091288
105
11966
K55
M
L
N
A
W
L
N
K
E
H
H
P
Q
E
R
Zebra Danio
Brachydanio rerio
NP_001005592
108
12193
R58
C
M
L
N
M
Y
L
R
S
Q
H
H
H
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20779
128
14724
K72
L
T
M
Y
A
A
F
K
D
H
K
K
H
M
S
Sea Urchin
Strong. purpuratus
XP_001192461
115
12958
M64
V
N
A
Y
K
G
E
M
E
H
K
A
H
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32799
129
15003
Y71
A
L
T
A
V
N
T
Y
F
V
E
K
E
H
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
93.5
83.6
N.A.
82.8
81.9
N.A.
56.8
65.1
55
62.3
N.A.
N.A.
N.A.
31.2
45.2
Protein Similarity:
100
98.1
94.5
87.2
N.A.
87.3
90
N.A.
59.6
74.3
66.9
72.4
N.A.
N.A.
N.A.
46.8
55.6
P-Site Identity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
13.3
13.3
0
13.3
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
80
N.A.
40
20
13.3
46.6
N.A.
N.A.
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
8
16
16
8
0
0
0
8
0
8
0
0
16
% A
% Cys:
8
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
24
0
8
0
16
31
54
% E
% Phe:
0
0
0
0
0
0
8
24
8
0
0
0
0
8
0
% F
% Gly:
24
0
0
0
0
8
0
0
0
0
0
0
0
39
0
% G
% His:
0
0
0
0
0
0
0
0
0
24
16
54
70
16
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
24
8
47
16
16
0
0
0
% K
% Leu:
8
16
16
8
47
8
16
8
47
0
0
0
0
0
0
% L
% Met:
8
16
16
47
8
0
0
8
0
0
0
0
0
8
0
% M
% Asn:
0
8
8
16
8
54
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
16
0
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
16
0
0
8
% R
% Ser:
8
0
47
0
0
0
0
0
8
0
47
0
8
0
8
% S
% Thr:
0
8
8
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
16
47
0
0
8
0
47
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
16
8
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _