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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A4
All Species:
34.24
Human Site:
S46
Identified Species:
57.95
UniProt:
P12235
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12235
NP_001142.2
298
33064
S46
Q
H
A
S
K
Q
I
S
A
E
K
Q
Y
K
G
Chimpanzee
Pan troglodytes
XP_517556
500
54130
S248
Q
H
A
S
K
Q
I
S
A
E
K
Q
Y
K
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532844
298
32743
S46
Q
H
A
S
K
Q
I
S
A
E
K
Q
Y
K
G
Cat
Felis silvestris
Mouse
Mus musculus
P48962
298
32886
S46
Q
H
A
S
K
Q
I
S
A
E
K
Q
Y
K
G
Rat
Rattus norvegicus
Q05962
298
32971
S46
Q
H
A
S
K
Q
I
S
A
E
K
Q
Y
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006443
298
32950
T46
Q
H
A
S
K
Q
I
T
A
E
K
Q
Y
K
G
Frog
Xenopus laevis
Q7T0U6
473
52371
K190
E
F
T
E
E
E
K
K
T
G
Q
W
W
K
Q
Zebra Danio
Brachydanio rerio
A2CEQ0
469
52693
S221
M
Q
V
H
A
T
R
S
N
S
M
G
I
A
G
Tiger Blowfish
Takifugu rubipres
NP_001037838
298
32796
T46
Q
H
A
S
K
Q
I
T
A
D
K
Q
Y
K
G
Fruit Fly
Dros. melanogaster
Q26365
312
34196
S61
Q
H
I
S
K
Q
I
S
P
D
K
Q
Y
K
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P04709
387
42373
R126
D
E
M
I
K
S
G
R
L
S
E
P
Y
K
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P40941
385
41727
R123
D
E
M
L
K
A
G
R
L
T
E
P
Y
K
G
Baker's Yeast
Sacchar. cerevisiae
P18239
318
34408
T62
D
E
M
L
K
Q
G
T
L
D
R
K
Y
A
G
Red Bread Mold
Neurospora crassa
P02723
313
33870
R52
D
E
M
I
R
A
G
R
L
D
R
R
Y
N
G
Conservation
Percent
Protein Identity:
100
58.7
N.A.
94.3
N.A.
95.3
95.6
N.A.
N.A.
93.6
22.4
21.3
87.9
75.9
N.A.
N.A.
N.A.
Protein Similarity:
100
59
N.A.
95.6
N.A.
98.3
98.3
N.A.
N.A.
96.9
37.2
35.6
94.3
84.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
93.3
6.6
13.3
86.6
80
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
40
13.3
100
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
44.9
N.A.
44.9
51.2
49.2
Protein Similarity:
N.A.
55
N.A.
54.8
64.7
64.2
P-Site Identity:
N.A.
26.6
N.A.
26.6
26.6
13.3
P-Site Similarity:
N.A.
33.3
N.A.
33.3
53.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
8
15
0
0
50
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% D
% Glu:
8
29
0
8
8
8
0
0
0
43
15
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
29
0
0
8
0
8
0
0
93
% G
% His:
0
58
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
15
0
0
58
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
79
0
8
8
0
0
58
8
0
79
0
% K
% Leu:
0
0
0
15
0
0
0
0
29
0
0
0
0
0
0
% L
% Met:
8
0
29
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
15
0
0
0
% P
% Gln:
58
8
0
0
0
65
0
0
0
0
8
58
0
0
8
% Q
% Arg:
0
0
0
0
8
0
8
22
0
0
15
8
0
0
0
% R
% Ser:
0
0
0
58
0
8
0
50
0
15
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
8
0
22
8
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
86
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _