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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A4 All Species: 19.72
Human Site: S7 Identified Species: 33.37
UniProt: P12235 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12235 NP_001142.2 298 33064 S7 _ M G D H A W S F L K D F L A
Chimpanzee Pan troglodytes XP_517556 500 54130 V209 L G D H G W E V S Y R T F L P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532844 298 32743 S7 _ M S D H A L S F L K D F L A
Cat Felis silvestris
Mouse Mus musculus P48962 298 32886 S7 _ M G D Q A L S F L K D F L A
Rat Rattus norvegicus Q05962 298 32971 S7 _ M G D Q A L S F L K D F L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001006443 298 32950 S7 _ M S D Q A L S F L K D F L A
Frog Xenopus laevis Q7T0U6 473 52371 T96 K K M K I A F T S L D K N K D
Zebra Danio Brachydanio rerio A2CEQ0 469 52693 M185 A E E K N T G M W W R H L V A
Tiger Blowfish Takifugu rubipres NP_001037838 298 32796 S7 _ M N E T A I S F A K D F L A
Fruit Fly Dros. melanogaster Q26365 312 34196 G22 G K D F D A V G F V K D F A A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P04709 387 42373 N86 P A E K G G K N F M I D F M M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P40941 385 41727 N83 P G E K G F T N F A I D F M M
Baker's Yeast Sacchar. cerevisiae P18239 318 34408 N22 P A P K K E S N F L I D F L M
Red Bread Mold Neurospora crassa P02723 313 33870 P12 Q K V L G M P P F V A D F L M
Conservation
Percent
Protein Identity: 100 58.7 N.A. 94.3 N.A. 95.3 95.6 N.A. N.A. 93.6 22.4 21.3 87.9 75.9 N.A. N.A. N.A.
Protein Similarity: 100 59 N.A. 95.6 N.A. 98.3 98.3 N.A. N.A. 96.9 37.2 35.6 94.3 84.6 N.A. N.A. N.A.
P-Site Identity: 100 13.3 N.A. 85.7 N.A. 85.7 85.7 N.A. N.A. 78.5 13.3 6.6 64.2 40 N.A. N.A. N.A.
P-Site Similarity: 100 20 N.A. 85.7 N.A. 85.7 85.7 N.A. N.A. 78.5 26.6 33.3 71.4 53.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 44.9 N.A. 44.9 51.2 49.2
Protein Similarity: N.A. 55 N.A. 54.8 64.7 64.2
P-Site Identity: N.A. 20 N.A. 20 33.3 26.6
P-Site Similarity: N.A. 40 N.A. 33.3 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 0 0 0 58 0 0 0 15 8 0 0 8 58 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 36 8 0 0 0 0 0 8 79 0 0 8 % D
% Glu: 0 8 22 8 0 8 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 8 8 0 79 0 0 0 86 0 0 % F
% Gly: 8 15 22 0 29 8 8 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 15 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 8 0 8 0 0 0 22 0 0 0 0 % I
% Lys: 8 22 0 36 8 0 8 0 0 0 50 8 0 8 0 % K
% Leu: 8 0 0 8 0 0 29 0 0 50 0 0 8 65 0 % L
% Met: 0 43 8 0 0 8 0 8 0 8 0 0 0 15 29 % M
% Asn: 0 0 8 0 8 0 0 22 0 0 0 0 8 0 0 % N
% Pro: 22 0 8 0 0 0 8 8 0 0 0 0 0 0 8 % P
% Gln: 8 0 0 0 22 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % R
% Ser: 0 0 15 0 0 0 8 43 15 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 8 8 8 8 0 0 0 8 0 0 0 % T
% Val: 0 0 8 0 0 0 8 8 0 15 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 8 8 0 8 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 43 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _