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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
F5
All Species:
1.21
Human Site:
Y1623
Identified Species:
2.96
UniProt:
P12259
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12259
NP_000121.2
2224
251671
Y1623
K
K
V
V
F
R
K
Y
L
D
S
T
F
T
K
Chimpanzee
Pan troglodytes
XP_513984
1812
205939
L1258
L
A
S
R
P
Y
S
L
H
A
H
G
L
S
Y
Rhesus Macaque
Macaca mulatta
XP_001093072
2190
247060
E1623
V
H
R
E
T
D
I
E
D
S
D
D
I
P
E
Dog
Lupus familis
XP_854412
1107
126364
G553
G
S
F
Y
K
T
P
G
R
R
T
P
P
P
S
Cat
Felis silvestris
Mouse
Mus musculus
O88783
2183
247212
R1591
L
D
S
T
F
T
S
R
D
P
R
A
E
Y
E
Rat
Rattus norvegicus
Q920H8
1157
129575
S603
Q
A
A
G
M
L
D
S
R
L
L
S
E
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513275
1390
155965
A836
F
P
H
S
S
L
T
A
F
M
Q
P
D
H
T
Chicken
Gallus gallus
XP_001231901
1880
212923
S1326
P
M
D
F
F
M
K
S
P
L
R
E
A
F
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007209
2101
238294
M1547
G
V
K
Y
L
K
Q
M
E
G
L
S
Y
D
D
Tiger Blowfish
Takifugu rubipres
NP_001027922
1639
185185
S1085
N
N
A
S
R
P
Y
S
F
H
L
H
G
V
Y
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.2
87.3
20.2
N.A.
70.2
21.7
N.A.
22.7
29
N.A.
37.7
27.1
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80.8
89.6
31.2
N.A.
80.4
32.5
N.A.
36.5
46
N.A.
56.7
42.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
0
N.A.
6.6
0
N.A.
0
13.3
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
6.6
6.6
N.A.
13.3
13.3
N.A.
0
13.3
N.A.
26.6
0
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
20
0
0
0
0
10
0
10
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
10
10
0
20
10
10
10
10
20
10
% D
% Glu:
0
0
0
10
0
0
0
10
10
0
0
10
20
0
20
% E
% Phe:
10
0
10
10
30
0
0
0
20
0
0
0
10
10
0
% F
% Gly:
20
0
0
10
0
0
0
10
0
10
0
10
10
0
0
% G
% His:
0
10
10
0
0
0
0
0
10
10
10
10
0
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% I
% Lys:
10
10
10
0
10
10
20
0
0
0
0
0
0
0
10
% K
% Leu:
20
0
0
0
10
20
0
10
10
20
30
0
10
0
0
% L
% Met:
0
10
0
0
10
10
0
10
0
10
0
0
0
0
10
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
0
10
10
10
0
10
10
0
20
10
20
0
% P
% Gln:
10
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
10
10
10
10
0
10
20
10
20
0
0
0
0
% R
% Ser:
0
10
20
20
10
0
20
30
0
10
10
20
0
10
10
% S
% Thr:
0
0
0
10
10
20
10
0
0
0
10
10
0
10
10
% T
% Val:
10
10
10
10
0
0
0
0
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
10
10
10
0
0
0
0
10
10
20
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _