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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTHLH All Species: 21.21
Human Site: S26 Identified Species: 66.67
UniProt: P12272 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12272 NP_002811.1 177 20194 S26 A V P S C G R S V E G L S R R
Chimpanzee Pan troglodytes XP_001141862 196 22376 S26 A V P S C G R S V E G L S R R
Rhesus Macaque Macaca mulatta XP_001104008 177 20165 S26 A V P S C G R S V E G L S R R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P22858 175 20081 S26 S V P S R G R S V E G L G R R
Rat Rattus norvegicus P13085 177 20185 S26 S V P S R G R S V E G L G R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520951 183 20466 P34 S V P T A G R P G E G I S R R
Chicken Gallus gallus P17251 176 20208 S27 S V P S Y G R S V E G I S R R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001019798 198 21912 P30 P V P H H G R P V D A L S S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 99.4 N.A. N.A. 86.4 88.6 N.A. 70.4 73.4 N.A. 29.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 90.3 99.4 N.A. N.A. 88.1 90.4 N.A. 79.7 81.9 N.A. 43.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 N.A. N.A. 80 80 N.A. 60 80 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 86.6 86.6 N.A. 80 93.3 N.A. 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 0 0 0 13 0 0 0 0 0 13 0 0 0 0 % A
% Cys: 0 0 0 0 38 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 88 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 100 0 0 13 0 88 0 25 0 0 % G
% His: 0 0 0 13 13 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 13 0 100 0 0 0 0 25 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 25 0 100 0 0 0 0 0 0 88 100 % R
% Ser: 50 0 0 75 0 0 0 75 0 0 0 0 75 13 0 % S
% Thr: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 100 0 0 0 0 0 0 88 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _