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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CKB All Species: 57.88
Human Site: S239 Identified Species: 90.95
UniProt: P12277 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12277 NP_001814.2 381 42644 S239 E D H L R V I S M Q K G G N M
Chimpanzee Pan troglodytes XP_510185 464 51502 S322 E D H L R V I S M Q K G G N M
Rhesus Macaque Macaca mulatta XP_001112108 381 42634 S239 E D H L R V I S M Q K G G N M
Dog Lupus familis XP_537561 394 44036 S252 E D H L R V I S M Q K G G N M
Cat Felis silvestris
Mouse Mus musculus Q04447 381 42695 S239 E D H L R V I S M Q K G G N M
Rat Rattus norvegicus P07335 381 42707 S239 E D H L R V I S M Q K G G N M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508143 326 36755 W218 T K N Y E F M W N P H L G Y I
Chicken Gallus gallus P05122 381 42852 S239 E D H L R V I S M Q K G G N M
Frog Xenopus laevis NP_001080363 376 42223 S234 E D H L R V I S M Q K G G N M
Zebra Danio Brachydanio rerio NP_775329 381 42865 S239 E D H L R V I S M Q K G G N M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48610 356 39848 S232 E D H L R I I S M Q Q G G D L
Honey Bee Apis mellifera O61367 355 39990 S231 E D H L R I I S M Q M G G D L
Nematode Worm Caenorhab. elegans Q27535 360 40364 S236 E D H L R I I S M Q N G G N V
Sea Urchin Strong. purpuratus P18294 1174 130851 S1027 E D H T R V I S M E K S G N M
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001169054 381 42707 S239 E D H L R V I S M Q K G G N M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.9 99.2 94.4 N.A. 96.5 96.5 N.A. 77.9 90.5 83.1 85.8 N.A. 42.7 40.9 37.7 22.4
Protein Similarity: 100 82.1 100 95.9 N.A. 98.6 98.4 N.A. 83.7 96.3 92.3 93.1 N.A. 59 58.7 55.9 28.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 100 100 100 N.A. 73.3 73.3 80 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 100 100 100 N.A. 100 93.3 93.3 86.6
Percent
Protein Identity: N.A. 96.5 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 98.4 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 100 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 100 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 94 0 0 0 0 0 0 0 0 0 0 0 14 0 % D
% Glu: 94 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 87 100 0 0 % G
% His: 0 0 94 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 20 94 0 0 0 0 0 0 0 7 % I
% Lys: 0 7 0 0 0 0 0 0 0 0 74 0 0 0 0 % K
% Leu: 0 0 0 87 0 0 0 0 0 0 0 7 0 0 14 % L
% Met: 0 0 0 0 0 0 7 0 94 0 7 0 0 0 74 % M
% Asn: 0 0 7 0 0 0 0 0 7 0 7 0 0 80 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 87 7 0 0 0 0 % Q
% Arg: 0 0 0 0 94 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 94 0 0 0 7 0 0 0 % S
% Thr: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 74 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _