Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CKB All Species: 41.21
Human Site: T35 Identified Species: 64.76
UniProt: P12277 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12277 NP_001814.2 381 42644 T35 N H M A K V L T P E L Y A E L
Chimpanzee Pan troglodytes XP_510185 464 51502 T118 N H M A K V L T P E L Y A E L
Rhesus Macaque Macaca mulatta XP_001112108 381 42634 T35 N H M A K V L T P E L Y A E L
Dog Lupus familis XP_537561 394 44036 T35 N H M A K V L T P E L Y A E L
Cat Felis silvestris
Mouse Mus musculus Q04447 381 42695 T35 N H M A K V L T P E L Y A E L
Rat Rattus norvegicus P07335 381 42707 T35 N H M A K V L T P E L Y A E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508143 326 36755 E28 A G D E E S Y E V F K E L F D
Chicken Gallus gallus P05122 381 42852 T35 N H M A K V L T L D L Y K K L
Frog Xenopus laevis NP_001080363 376 42223 M33 A K V L T L D M Y K K L R S R
Zebra Danio Brachydanio rerio NP_775329 381 42865 T35 N H M A K V L T P E M Y A N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48610 356 39848 K32 L L K K Y L T K E V F D N L K
Honey Bee Apis mellifera O61367 355 39990 K32 L L K K Y L S K D V F D Q L K
Nematode Worm Caenorhab. elegans Q27535 360 40364 T33 S L L K K H L T K D V V A K N
Sea Urchin Strong. purpuratus P18294 1174 130851 T449 N H L A H C L T Y D I W K S L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001169054 381 42707 T35 N H M A K V L T P E L Y A E L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.9 99.2 94.4 N.A. 96.5 96.5 N.A. 77.9 90.5 83.1 85.8 N.A. 42.7 40.9 37.7 22.4
Protein Similarity: 100 82.1 100 95.9 N.A. 98.6 98.4 N.A. 83.7 96.3 92.3 93.1 N.A. 59 58.7 55.9 28.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 73.3 0 86.6 N.A. 0 0 26.6 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 86.6 20 93.3 N.A. 6.6 6.6 60 66.6
Percent
Protein Identity: N.A. 96.5 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 98.4 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 100 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 100 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 67 0 0 0 0 0 0 0 0 60 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 7 0 7 20 0 14 0 0 7 % D
% Glu: 0 0 0 7 7 0 0 7 7 54 0 7 0 47 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 14 0 0 7 0 % F
% Gly: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 67 0 0 7 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 7 14 20 67 0 0 14 7 7 14 0 14 14 14 % K
% Leu: 14 20 14 7 0 20 74 0 7 0 54 7 7 14 67 % L
% Met: 0 0 60 0 0 0 0 7 0 0 7 0 0 0 0 % M
% Asn: 67 0 0 0 0 0 0 0 0 0 0 0 7 7 7 % N
% Pro: 0 0 0 0 0 0 0 0 54 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % R
% Ser: 7 0 0 0 0 7 7 0 0 0 0 0 0 14 0 % S
% Thr: 0 0 0 0 7 0 7 74 0 0 0 0 0 0 0 % T
% Val: 0 0 7 0 0 60 0 0 7 14 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 14 0 7 0 14 0 0 60 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _