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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANXA3
All Species:
22.73
Human Site:
Y133
Identified Species:
62.5
UniProt:
P12429
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12429
NP_005130.1
323
36375
Y133
K
D
I
S
Q
A
Y
Y
T
V
Y
K
K
S
L
Chimpanzee
Pan troglodytes
A5A6M2
346
38724
R157
R
D
I
N
R
V
Y
R
E
E
L
K
R
D
L
Rhesus Macaque
Macaca mulatta
XP_001092115
323
36408
Y133
K
E
I
S
Q
A
Y
Y
T
I
Y
K
K
S
L
Dog
Lupus familis
XP_535624
325
36355
Y135
K
E
I
A
Q
A
Y
Y
T
V
Y
K
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
O35639
323
36352
Y133
K
E
I
S
Q
A
Y
Y
T
V
Y
K
K
S
L
Rat
Rattus norvegicus
P14669
324
36345
Y134
K
E
I
S
Q
A
Y
Y
T
A
Y
K
K
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P17153
321
36180
Y133
K
Q
V
Y
M
Q
E
Y
E
A
N
L
E
D
K
Frog
Xenopus laevis
NP_001085527
323
35780
Y133
K
E
V
G
D
A
Y
Y
T
V
Y
G
K
S
L
Zebra Danio
Brachydanio rerio
NP_001007303
340
37635
L149
K
A
M
R
D
A
Y
L
A
E
T
G
R
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
97.2
89.2
N.A.
89.1
85.1
N.A.
N.A.
50.4
73.6
52.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.5
99
93.8
N.A.
95
91.3
N.A.
N.A.
69
85.7
70
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
86.6
86.6
N.A.
93.3
80
N.A.
N.A.
13.3
66.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
100
100
N.A.
100
93.3
N.A.
N.A.
26.6
80
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
12
0
78
0
0
12
23
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
23
0
0
23
0
0
0
0
0
0
0
0
23
0
% D
% Glu:
0
56
0
0
0
0
12
0
23
23
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
0
0
23
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
67
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
89
0
0
0
0
0
0
0
0
0
0
67
67
0
12
% K
% Leu:
0
0
0
0
0
0
0
12
0
0
12
12
0
0
89
% L
% Met:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
0
0
0
0
12
0
0
23
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
56
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
12
12
0
0
12
0
0
0
0
23
0
0
% R
% Ser:
0
0
0
45
0
0
0
0
0
0
0
0
0
56
0
% S
% Thr:
0
0
0
0
0
0
0
0
67
0
12
0
0
0
0
% T
% Val:
0
0
23
0
0
12
0
0
0
45
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
89
78
0
0
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _