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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CKMT1A All Species: 12.42
Human Site: S41 Identified Species: 21.03
UniProt: P12532 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12532 NP_001015001.1 417 47037 S41 P E P V R A A S E R R R L Y P
Chimpanzee Pan troglodytes XP_517671 356 40461 L24 V T P N G Y T L D Q C I Q T G
Rhesus Macaque Macaca mulatta XP_001102013 767 82902 S391 P E P V R A A S E R R R L Y P
Dog Lupus familis XP_535451 417 47057 S41 P E P V R A A S E R R R L Y P
Cat Felis silvestris
Mouse Mus musculus P30275 418 46985 A42 E S V G A A A A E R R R L Y P
Rat Rattus norvegicus P25809 418 47010 G42 E S V R A A T G E R R R L Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516190 602 66708 G41 P D P L R A A G D R R R L Y P
Chicken Gallus gallus P70079 417 47085 E41 R D T V S A G E R Q R R R Y P
Frog Xenopus laevis NP_001080463 418 46838 S42 D A I S A D T S H K R R M Y P
Zebra Danio Brachydanio rerio XP_002663507 417 46785 D41 D S A A I S A D E K R K L Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48610 356 39848 S24 L A A S D S K S L L K K Y L T
Honey Bee Apis mellifera O61367 355 39990 K23 K L S S S D S K S L L K K Y L
Nematode Worm Caenorhab. elegans Q10454 396 44149 D43 E G M S V S P D V I A K I E E
Sea Urchin Strong. purpuratus P18294 1174 130851 R796 D I L P Q Q C R P K P P I K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.1 54.2 98.3 N.A. 96.6 95.9 N.A. 65.2 88.4 83 79.8 N.A. 37.8 37.4 38.6 24.4
Protein Similarity: 100 78.6 54.3 99.2 N.A. 98.3 97.8 N.A. 68.1 93 91.1 90.4 N.A. 54.9 55.1 53.7 30
P-Site Identity: 100 6.6 100 100 N.A. 60 53.3 N.A. 73.3 40 33.3 40 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 20 100 100 N.A. 66.6 53.3 N.A. 93.3 53.3 46.6 60 N.A. 26.6 20 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 15 8 22 50 43 8 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % C
% Asp: 22 15 0 0 8 15 0 15 15 0 0 0 0 0 0 % D
% Glu: 22 22 0 0 0 0 0 8 43 0 0 0 0 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 8 0 8 15 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 8 0 0 0 0 8 0 8 15 0 0 % I
% Lys: 8 0 0 0 0 0 8 8 0 22 8 29 8 8 0 % K
% Leu: 8 8 8 8 0 0 0 8 8 15 8 0 50 8 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 29 0 36 8 0 0 8 0 8 0 8 8 0 0 72 % P
% Gln: 0 0 0 0 8 8 0 0 0 15 0 0 8 0 0 % Q
% Arg: 8 0 0 8 29 0 0 8 8 43 65 58 8 0 0 % R
% Ser: 0 22 8 29 15 22 8 36 8 0 0 0 0 0 0 % S
% Thr: 0 8 8 0 0 0 22 0 0 0 0 0 0 8 8 % T
% Val: 8 0 15 29 8 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 8 72 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _