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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GZMA
All Species:
13.33
Human Site:
S200
Identified Species:
41.9
UniProt:
P12544
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12544
NP_006135.1
262
28969
S200
M
N
M
V
C
A
G
S
L
R
G
G
R
D
S
Chimpanzee
Pan troglodytes
XP_001148261
262
28937
S200
M
N
M
V
C
A
G
S
L
R
G
G
R
D
S
Rhesus Macaque
Macaca mulatta
XP_001097639
262
28823
S200
M
N
M
V
C
A
G
S
L
R
G
G
K
D
S
Dog
Lupus familis
XP_544335
260
28538
S198
L
N
M
I
C
A
G
S
L
N
G
G
K
D
S
Cat
Felis silvestris
Mouse
Mus musculus
P11032
260
28581
D199
L
N
M
I
C
A
G
D
L
R
G
G
K
D
S
Rat
Rattus norvegicus
P49864
258
28446
D196
K
D
M
I
C
A
G
D
R
R
G
E
K
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989788
260
28466
R197
M
I
C
A
G
S
K
R
G
D
K
D
S
C
R
Frog
Xenopus laevis
Q63ZK0
263
29212
K201
M
I
C
A
I
E
A
K
K
D
S
C
E
G
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
91.5
72.9
N.A.
67.9
45
N.A.
N.A.
51.9
34.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
95
86.2
N.A.
80.5
61.8
N.A.
N.A.
68.6
57.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
53.3
N.A.
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
73.3
N.A.
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
25
0
75
13
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
25
0
75
0
0
0
0
0
0
13
0
13
0
% C
% Asp:
0
13
0
0
0
0
0
25
0
25
0
13
0
75
13
% D
% Glu:
0
0
0
0
0
13
0
0
0
0
0
13
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
0
75
0
13
0
75
63
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
0
38
13
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
13
0
0
0
0
0
13
13
13
0
13
0
50
0
0
% K
% Leu:
25
0
0
0
0
0
0
0
63
0
0
0
0
0
0
% L
% Met:
63
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
63
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
13
63
0
0
25
0
13
% R
% Ser:
0
0
0
0
0
13
0
50
0
0
13
0
13
0
75
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _