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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BMP2
All Species:
19.39
Human Site:
T181
Identified Species:
38.79
UniProt:
P12643
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12643
NP_001191.1
396
44702
T181
Y
E
I
I
K
P
A
T
A
N
S
K
F
P
V
Chimpanzee
Pan troglodytes
XP_514508
398
44777
T183
Y
E
I
I
K
P
A
T
A
N
S
K
F
P
V
Rhesus Macaque
Macaca mulatta
XP_001115987
396
44746
T181
Y
E
I
I
K
P
A
T
A
N
S
K
F
P
V
Dog
Lupus familis
XP_534351
395
44768
A180
Y
E
I
I
K
P
A
A
A
N
L
K
F
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P21274
394
44495
A179
Y
E
I
I
K
P
A
A
A
N
L
K
F
P
V
Rat
Rattus norvegicus
P49001
393
44364
T178
Y
E
I
I
K
P
A
T
A
S
S
K
F
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514564
689
75672
T474
Y
E
I
I
K
P
A
T
A
I
S
K
D
P
V
Chicken
Gallus gallus
Q90751
353
40328
S163
H
N
A
S
K
W
E
S
S
D
V
T
P
A
V
Frog
Xenopus laevis
P30884
398
45597
A183
Y
D
I
V
K
P
A
A
A
A
S
R
G
P
V
Zebra Danio
Brachydanio rerio
P35621
355
40183
K161
V
T
H
E
S
S
R
K
L
L
Q
S
Q
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
V358
Y
D
I
T
R
V
G
V
R
G
Q
R
E
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
I174
S
R
T
R
L
N
S
I
V
S
L
K
D
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.7
94.4
N.A.
91.1
91.4
N.A.
49.2
73.7
72.8
33
N.A.
30.6
N.A.
N.A.
31.3
Protein Similarity:
100
99.2
99.4
96.4
N.A.
95.7
95.9
N.A.
53.2
79.8
82.6
48.2
N.A.
44.3
N.A.
N.A.
49.7
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
86.6
13.3
60
0
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
100
N.A.
86.6
40
80
6.6
N.A.
40
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
67
25
67
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
0
0
0
0
9
0
0
17
0
0
% D
% Glu:
0
59
0
9
0
0
9
0
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
9
0
0
9
0
0
% G
% His:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
75
59
0
0
0
9
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
75
0
0
9
0
0
0
67
0
9
0
% K
% Leu:
0
0
0
0
9
0
0
0
9
9
25
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
0
0
0
42
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
67
0
0
0
0
0
0
9
75
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
9
0
0
% Q
% Arg:
0
9
0
9
9
0
9
0
9
0
0
17
0
0
9
% R
% Ser:
9
0
0
9
9
9
9
9
9
17
50
9
0
0
9
% S
% Thr:
0
9
9
9
0
0
0
42
0
0
0
9
0
9
0
% T
% Val:
9
0
0
9
0
9
0
9
9
0
9
0
0
0
75
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _