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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BMP4
All Species:
16.97
Human Site:
S218
Identified Species:
33.94
UniProt:
P12644
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12644
NP_001193.2
408
46555
S218
R
W
E
T
F
D
V
S
P
A
V
L
R
W
T
Chimpanzee
Pan troglodytes
XP_509954
455
51567
S265
R
W
E
T
F
D
V
S
P
A
V
L
R
W
T
Rhesus Macaque
Macaca mulatta
XP_001084317
408
46516
S218
R
W
E
T
F
D
V
S
P
A
V
L
R
W
T
Dog
Lupus familis
XP_851628
409
46679
S219
R
W
E
T
F
D
V
S
P
A
V
L
R
W
T
Cat
Felis silvestris
Mouse
Mus musculus
P21275
408
46478
V218
T
R
W
E
T
F
D
V
S
P
A
V
L
R
W
Rat
Rattus norvegicus
Q06826
408
46522
V218
T
R
W
E
T
F
D
V
S
P
A
V
L
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514564
689
75672
S499
H
N
A
S
K
W
E
S
F
D
V
T
P
A
V
Chicken
Gallus gallus
Q90752
405
46039
F215
N
V
T
R
W
E
T
F
D
V
S
P
A
V
I
Frog
Xenopus laevis
P30885
401
45970
F211
N
V
T
Q
W
E
S
F
D
V
S
P
A
I
M
Zebra Danio
Brachydanio rerio
P35621
355
40183
S169
L
L
Q
S
Q
T
L
S
P
G
A
H
A
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
P397
V
D
R
W
L
A
S
P
Q
R
N
Y
G
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
S204
A
G
T
I
D
I
L
S
T
V
N
S
W
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.6
99.5
97.8
N.A.
97.3
96.5
N.A.
38.4
84
80.3
31.6
N.A.
30.6
N.A.
N.A.
31.6
Protein Similarity:
100
88.5
99.5
99.2
N.A.
98.5
97.7
N.A.
46.2
90.1
88.7
48.7
N.A.
44
N.A.
N.A.
48.5
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
13.3
0
0
13.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
6.6
6.6
N.A.
20
13.3
13.3
33.3
N.A.
0
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
9
0
0
0
34
25
0
25
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
34
17
0
17
9
0
0
0
0
0
% D
% Glu:
0
0
34
17
0
17
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
34
17
0
17
9
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
9
0
0
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
9
0
9
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
9
0
0
9
0
17
0
0
0
0
34
17
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
17
9
0
0
0
0
0
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
42
17
0
17
9
0
0
% P
% Gln:
0
0
9
9
9
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
34
17
9
9
0
0
0
0
0
9
0
0
34
25
0
% R
% Ser:
0
0
0
17
0
0
17
59
17
0
17
9
0
9
9
% S
% Thr:
17
0
25
34
17
9
9
0
9
0
0
9
0
0
34
% T
% Val:
9
17
0
0
0
0
34
17
0
25
42
17
0
9
17
% V
% Trp:
0
34
17
9
17
9
0
0
0
0
0
0
9
34
17
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _