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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BMP4
All Species:
13.64
Human Site:
S257
Identified Species:
27.27
UniProt:
P12644
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12644
NP_001193.2
408
46555
S257
Q
H
V
R
I
S
R
S
L
P
Q
G
S
G
N
Chimpanzee
Pan troglodytes
XP_509954
455
51567
S304
Q
H
V
R
I
S
R
S
L
P
Q
G
S
G
N
Rhesus Macaque
Macaca mulatta
XP_001084317
408
46516
S257
Q
H
V
R
I
S
R
S
L
P
Q
G
S
G
N
Dog
Lupus familis
XP_851628
409
46679
S258
Q
H
V
R
I
S
R
S
L
P
Q
G
S
G
D
Cat
Felis silvestris
Mouse
Mus musculus
P21275
408
46478
R257
G
Q
H
V
R
I
S
R
S
L
P
Q
G
S
G
Rat
Rattus norvegicus
Q06826
408
46522
R257
G
Q
H
V
R
I
S
R
S
L
P
Q
G
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514564
689
75672
R538
G
V
S
E
R
H
V
R
I
S
R
S
L
H
Q
Chicken
Gallus gallus
Q90752
405
46039
I254
H
Q
G
K
H
V
R
I
S
R
S
L
P
Q
G
Frog
Xenopus laevis
P30885
401
45970
I250
Y
Q
G
K
H
V
R
I
S
R
S
L
L
P
Q
Zebra Danio
Brachydanio rerio
P35621
355
40183
M208
Q
V
M
H
L
N
N
M
L
H
D
H
A
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
H436
E
A
H
E
R
W
Q
H
K
Q
P
L
L
F
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
G243
S
Q
V
I
K
E
L
G
A
I
S
K
K
C
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.6
99.5
97.8
N.A.
97.3
96.5
N.A.
38.4
84
80.3
31.6
N.A.
30.6
N.A.
N.A.
31.6
Protein Similarity:
100
88.5
99.5
99.2
N.A.
98.5
97.7
N.A.
46.2
90.1
88.7
48.7
N.A.
44
N.A.
N.A.
48.5
P-Site Identity:
100
100
100
93.3
N.A.
0
0
N.A.
0
6.6
6.6
13.3
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
0
0
N.A.
13.3
13.3
13.3
40
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% D
% Glu:
9
0
0
17
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
25
0
17
0
0
0
0
9
0
0
0
34
17
34
25
% G
% His:
9
34
25
9
17
9
0
9
0
9
0
9
0
9
0
% H
% Ile:
0
0
0
9
34
17
0
17
9
9
0
0
0
0
0
% I
% Lys:
0
0
0
17
9
0
0
0
9
0
0
9
9
0
0
% K
% Leu:
0
0
0
0
9
0
9
0
42
17
0
25
25
0
0
% L
% Met:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
25
% N
% Pro:
0
0
0
0
0
0
0
0
0
34
25
0
9
9
0
% P
% Gln:
42
42
0
0
0
0
9
0
0
9
34
17
0
9
17
% Q
% Arg:
0
0
0
34
34
0
50
25
0
17
9
0
0
0
0
% R
% Ser:
9
0
9
0
0
34
17
34
34
9
25
9
34
17
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% T
% Val:
0
17
42
17
0
17
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _