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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BMP4 All Species: 14.24
Human Site: T274 Identified Species: 28.48
UniProt: P12644 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12644 NP_001193.2 408 46555 T274 Q L R P L L V T F G H D G R G
Chimpanzee Pan troglodytes XP_509954 455 51567 T321 Q L R P L L V T F G H D G R G
Rhesus Macaque Macaca mulatta XP_001084317 408 46516 T274 Q L R P L L V T F G H D G R G
Dog Lupus familis XP_851628 409 46679 T275 Q L R P L L V T F G H D G R G
Cat Felis silvestris
Mouse Mus musculus P21275 408 46478 V274 A Q L R P L L V T F G H D G R
Rat Rattus norvegicus Q06826 408 46522 V274 A Q L R P L L V T F G H D G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514564 689 75672 P555 Q S W P Q I R P L L V T F G H
Chicken Gallus gallus Q90752 405 46039 P271 G D W A Q L R P L L V T F G H
Frog Xenopus laevis P30885 401 45970 P267 A D W S Q M R P L L I T F S H
Zebra Danio Brachydanio rerio P35621 355 40183 V225 P D I H A T L V V V S L N P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07713 588 65849 R453 D D G R H K A R S I R D V S G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P48970 395 43818 Y260 L I V T S S E Y R Q C S K R N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 99.5 97.8 N.A. 97.3 96.5 N.A. 38.4 84 80.3 31.6 N.A. 30.6 N.A. N.A. 31.6
Protein Similarity: 100 88.5 99.5 99.2 N.A. 98.5 97.7 N.A. 46.2 90.1 88.7 48.7 N.A. 44 N.A. N.A. 48.5
P-Site Identity: 100 100 100 100 N.A. 6.6 6.6 N.A. 13.3 6.6 0 0 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 13.3 13.3 N.A. 20 6.6 6.6 6.6 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 0 9 9 0 9 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 9 34 0 0 0 0 0 0 0 0 0 42 17 0 0 % D
% Glu: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 34 17 0 0 25 0 0 % F
% Gly: 9 0 9 0 0 0 0 0 0 34 17 0 34 34 42 % G
% His: 0 0 0 9 9 0 0 0 0 0 34 17 0 0 25 % H
% Ile: 0 9 9 0 0 9 0 0 0 9 9 0 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 0 % K
% Leu: 9 34 17 0 34 59 25 0 25 25 0 9 0 0 9 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % N
% Pro: 9 0 0 42 17 0 0 25 0 0 0 0 0 9 0 % P
% Gln: 42 17 0 0 25 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 0 34 25 0 0 25 9 9 0 9 0 0 42 17 % R
% Ser: 0 9 0 9 9 9 0 0 9 0 9 9 0 17 0 % S
% Thr: 0 0 0 9 0 9 0 34 17 0 0 25 0 0 0 % T
% Val: 0 0 9 0 0 0 34 25 9 9 17 0 9 0 0 % V
% Trp: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _