KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BMP4
All Species:
26.36
Human Site:
Y106
Identified Species:
52.73
UniProt:
P12644
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12644
NP_001193.2
408
46555
Y106
I
H
S
T
G
L
E
Y
P
E
R
P
A
S
R
Chimpanzee
Pan troglodytes
XP_509954
455
51567
Y153
I
H
S
T
G
L
E
Y
P
E
R
P
A
S
R
Rhesus Macaque
Macaca mulatta
XP_001084317
408
46516
Y106
I
H
S
A
G
L
E
Y
P
E
R
P
A
S
R
Dog
Lupus familis
XP_851628
409
46679
Y107
I
H
S
I
G
L
E
Y
P
E
R
P
A
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P21275
408
46478
Y107
S
Q
G
T
G
L
E
Y
P
E
R
P
A
S
R
Rat
Rattus norvegicus
Q06826
408
46522
Y107
S
Q
G
T
G
L
E
Y
P
E
R
P
A
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514564
689
75672
R391
E
E
P
A
M
D
Y
R
L
E
R
A
A
S
R
Chicken
Gallus gallus
Q90752
405
46039
Y107
L
Q
E
I
S
L
Q
Y
P
E
R
S
A
S
R
Frog
Xenopus laevis
P30885
401
45970
Y104
L
H
D
I
S
M
E
Y
P
E
T
P
T
S
R
Zebra Danio
Brachydanio rerio
P35621
355
40183
V69
Q
T
V
N
D
P
C
V
V
S
E
Y
G
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
N127
N
K
S
K
Q
L
V
N
K
P
N
H
N
K
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
R90
K
E
E
E
E
D
G
R
P
C
S
E
T
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.6
99.5
97.8
N.A.
97.3
96.5
N.A.
38.4
84
80.3
31.6
N.A.
30.6
N.A.
N.A.
31.6
Protein Similarity:
100
88.5
99.5
99.2
N.A.
98.5
97.7
N.A.
46.2
90.1
88.7
48.7
N.A.
44
N.A.
N.A.
48.5
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
33.3
53.3
53.3
6.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
80
N.A.
33.3
66.6
66.6
6.6
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
0
0
0
0
0
9
67
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
17
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
17
17
9
9
0
59
0
0
75
9
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
50
0
9
0
0
0
0
0
9
0
0
% G
% His:
0
42
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
34
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
9
0
0
0
0
9
0
0
0
0
17
0
% K
% Leu:
17
0
0
0
0
67
0
0
9
0
0
0
0
0
9
% L
% Met:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
0
0
9
0
0
0
9
0
0
9
0
9
0
0
% N
% Pro:
0
0
9
0
0
9
0
0
75
9
0
59
0
0
0
% P
% Gln:
9
25
0
0
9
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
17
0
0
67
0
0
0
84
% R
% Ser:
17
0
42
0
17
0
0
0
0
9
9
9
0
75
0
% S
% Thr:
0
9
0
34
0
0
0
0
0
0
9
0
17
0
0
% T
% Val:
0
0
9
0
0
0
9
9
9
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
67
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _