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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDHA
All Species:
20
Human Site:
S370
Identified Species:
40
UniProt:
P12694
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12694
NP_000700.1
445
50471
S370
R
L
R
H
Y
L
L
S
Q
G
W
W
D
E
E
Chimpanzee
Pan troglodytes
A5A6H9
445
50498
S370
R
L
R
H
Y
L
L
S
Q
G
W
W
D
E
E
Rhesus Macaque
Macaca mulatta
XP_001101959
445
50521
S370
R
L
R
H
Y
L
L
S
Q
G
W
W
D
E
E
Dog
Lupus familis
XP_866392
446
50555
S371
R
L
R
H
Y
L
Q
S
R
G
W
W
D
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P50136
442
50352
N367
R
L
R
Q
Y
L
L
N
Q
G
W
W
D
E
E
Rat
Rattus norvegicus
P11960
441
50146
N366
R
L
R
Q
Y
L
L
N
Q
G
W
W
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517857
495
54892
S420
R
L
R
H
H
L
L
S
K
G
W
W
G
E
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019590
446
50761
A371
R
L
R
H
Y
M
T
A
R
D
W
W
G
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649905
439
49725
H364
K
L
K
R
Y
M
V
H
K
G
W
F
D
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52899
397
43773
D333
E
E
E
L
K
A
I
D
K
E
V
R
K
E
V
Sea Urchin
Strong. purpuratus
XP_788716
411
46846
M347
I
D
T
E
K
A
W
M
A
E
T
K
K
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P52901
389
43041
S325
R
I
K
K
L
V
L
S
H
D
L
A
T
E
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.6
94.3
N.A.
91.6
92.8
N.A.
61
N.A.
N.A.
77.8
N.A.
54.8
N.A.
24.7
61.3
Protein Similarity:
100
99.7
99.3
96.8
N.A.
96.1
96.6
N.A.
71.3
N.A.
N.A.
86.5
N.A.
71.9
N.A.
38.8
76.6
P-Site Identity:
100
100
100
80
N.A.
86.6
86.6
N.A.
80
N.A.
N.A.
53.3
N.A.
40
N.A.
6.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
N.A.
80
N.A.
80
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
9
9
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
9
0
17
0
0
59
17
9
% D
% Glu:
9
9
9
9
0
0
0
0
0
17
0
0
0
84
59
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
67
0
0
17
0
0
% G
% His:
0
0
0
50
9
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
9
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
17
9
17
0
0
0
25
0
0
9
17
0
9
% K
% Leu:
0
75
0
9
9
59
59
0
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
17
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
17
0
0
9
0
42
0
0
0
0
0
0
% Q
% Arg:
75
0
67
9
0
0
0
0
17
0
0
9
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
9
0
0
0
9
0
9
0
9
% T
% Val:
0
0
0
0
0
9
9
0
0
0
9
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
75
67
0
0
0
% W
% Tyr:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _