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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDHA
All Species:
33.03
Human Site:
S386
Identified Species:
66.06
UniProt:
P12694
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12694
NP_000700.1
445
50471
S386
E
K
A
W
R
K
Q
S
R
R
K
V
M
E
A
Chimpanzee
Pan troglodytes
A5A6H9
445
50498
S386
E
K
A
W
R
K
Q
S
R
K
K
V
M
E
A
Rhesus Macaque
Macaca mulatta
XP_001101959
445
50521
S386
E
K
A
W
R
K
Q
S
R
K
K
V
M
E
A
Dog
Lupus familis
XP_866392
446
50555
S387
E
K
A
W
R
K
Q
S
R
K
K
V
M
E
A
Cat
Felis silvestris
Mouse
Mus musculus
P50136
442
50352
S383
E
K
A
W
R
K
Q
S
R
K
K
V
M
E
A
Rat
Rattus norvegicus
P11960
441
50146
S382
E
K
A
W
R
K
Q
S
R
K
K
V
M
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517857
495
54892
S436
E
K
T
W
R
K
Q
S
R
K
L
V
M
E
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019590
446
50761
S387
E
R
A
W
R
K
Q
S
R
K
L
V
M
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649905
439
49725
I380
E
N
E
Y
V
K
D
I
R
K
K
V
L
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52899
397
43773
T348
D
E
A
L
K
I
A
T
S
D
G
V
L
P
P
Sea Urchin
Strong. purpuratus
XP_788716
411
46846
E362
L
Q
E
F
Q
A
A
E
K
L
K
K
P
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P52901
389
43041
E340
E
L
K
D
M
E
K
E
I
R
K
E
V
D
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.6
94.3
N.A.
91.6
92.8
N.A.
61
N.A.
N.A.
77.8
N.A.
54.8
N.A.
24.7
61.3
Protein Similarity:
100
99.7
99.3
96.8
N.A.
96.1
96.6
N.A.
71.3
N.A.
N.A.
86.5
N.A.
71.9
N.A.
38.8
76.6
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
80
N.A.
N.A.
80
N.A.
33.3
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
93.3
N.A.
60
N.A.
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
0
0
9
17
0
0
0
0
0
0
0
67
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
9
0
0
9
0
0
0
9
9
% D
% Glu:
84
9
17
0
0
9
0
17
0
0
0
9
0
67
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
9
9
0
0
0
0
0
0
% I
% Lys:
0
59
9
0
9
75
9
0
9
67
75
9
0
9
0
% K
% Leu:
9
9
0
9
0
0
0
0
0
9
17
0
17
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
67
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
17
% P
% Gln:
0
9
0
0
9
0
67
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
0
0
67
0
0
0
75
17
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
9
0
0
0
0
9
0
% S
% Thr:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
84
9
0
0
% V
% Trp:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _