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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDHA
All Species:
23.64
Human Site:
S426
Identified Species:
47.27
UniProt:
P12694
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12694
NP_000700.1
445
50471
S426
Q
L
R
K
Q
Q
E
S
L
A
R
H
L
Q
T
Chimpanzee
Pan troglodytes
A5A6H9
445
50498
S426
Q
L
R
K
Q
Q
E
S
L
A
R
H
L
Q
T
Rhesus Macaque
Macaca mulatta
XP_001101959
445
50521
S426
Q
L
R
K
Q
Q
E
S
L
A
R
H
L
Q
T
Dog
Lupus familis
XP_866392
446
50555
A427
Q
L
R
K
Q
Q
E
A
L
A
R
H
L
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
P50136
442
50352
S423
Q
L
R
R
Q
Q
E
S
L
A
R
H
L
Q
T
Rat
Rattus norvegicus
P11960
441
50146
S422
Q
L
R
R
Q
Q
E
S
L
A
R
H
L
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517857
495
54892
A476
H
L
Q
K
Q
Q
D
A
L
A
R
H
L
K
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019590
446
50761
S427
H
I
A
K
Q
K
D
S
M
W
R
H
V
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649905
439
49725
E420
H
L
I
E
Q
R
S
E
L
E
K
H
I
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52899
397
43773
T379
R
G
A
T
I
D
E
T
I
V
Q
P
F
K
T
Sea Urchin
Strong. purpuratus
XP_788716
411
46846
K393
R
Q
M
D
E
M
K
K
H
V
E
K
H
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P52901
389
43041
G371
F
T
N
V
Y
V
K
G
F
G
T
E
S
F
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.6
94.3
N.A.
91.6
92.8
N.A.
61
N.A.
N.A.
77.8
N.A.
54.8
N.A.
24.7
61.3
Protein Similarity:
100
99.7
99.3
96.8
N.A.
96.1
96.6
N.A.
71.3
N.A.
N.A.
86.5
N.A.
71.9
N.A.
38.8
76.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
66.6
N.A.
N.A.
40
N.A.
26.6
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
73.3
N.A.
60
N.A.
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
17
0
59
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
9
17
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
9
0
59
9
0
9
9
9
0
9
9
% E
% Phe:
9
0
0
0
0
0
0
0
9
0
0
0
9
9
0
% F
% Gly:
0
9
0
0
0
0
0
9
0
9
0
0
0
0
9
% G
% His:
25
0
0
0
0
0
0
0
9
0
0
75
9
0
0
% H
% Ile:
0
9
9
0
9
0
0
0
9
0
0
0
9
0
0
% I
% Lys:
0
0
0
50
0
9
17
9
0
0
9
9
0
25
0
% K
% Leu:
0
67
0
0
0
0
0
0
67
0
0
0
59
0
0
% L
% Met:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
50
9
9
0
75
59
0
0
0
0
9
0
0
59
9
% Q
% Arg:
17
0
50
17
0
9
0
0
0
0
67
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
50
0
0
0
0
9
0
0
% S
% Thr:
0
9
0
9
0
0
0
9
0
0
9
0
0
0
67
% T
% Val:
0
0
0
9
0
9
0
0
0
17
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _