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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BCKDHA
All Species:
34.55
Human Site:
Y438
Identified Species:
69.09
UniProt:
P12694
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12694
NP_000700.1
445
50471
Y438
L
Q
T
Y
G
E
H
Y
P
L
D
H
F
D
K
Chimpanzee
Pan troglodytes
A5A6H9
445
50498
Y438
L
Q
T
Y
G
E
H
Y
P
L
D
H
F
D
K
Rhesus Macaque
Macaca mulatta
XP_001101959
445
50521
Y438
L
Q
T
Y
G
E
H
Y
P
L
E
H
F
D
K
Dog
Lupus familis
XP_866392
446
50555
Y439
L
Q
T
Y
G
E
H
Y
P
L
D
H
F
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P50136
442
50352
Y435
L
Q
T
Y
G
E
H
Y
P
L
D
H
F
E
K
Rat
Rattus norvegicus
P11960
441
50146
Y434
L
Q
T
Y
G
E
H
Y
P
L
D
H
F
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517857
495
54892
Y488
L
K
T
Y
G
E
H
Y
P
L
D
H
F
E
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019590
446
50761
Y439
V
Q
Q
Y
K
E
H
Y
P
L
D
H
Y
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649905
439
49725
Y432
I
E
A
H
K
E
H
Y
P
L
K
D
F
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52899
397
43773
Sea Urchin
Strong. purpuratus
XP_788716
411
46846
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P52901
389
43041
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.6
94.3
N.A.
91.6
92.8
N.A.
61
N.A.
N.A.
77.8
N.A.
54.8
N.A.
24.7
61.3
Protein Similarity:
100
99.7
99.3
96.8
N.A.
96.1
96.6
N.A.
71.3
N.A.
N.A.
86.5
N.A.
71.9
N.A.
38.8
76.6
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
100
N.A.
80
N.A.
N.A.
66.6
N.A.
46.6
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
N.A.
86.6
N.A.
73.3
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
59
9
0
34
0
% D
% Glu:
0
9
0
0
0
75
0
0
0
0
9
0
0
42
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% F
% Gly:
0
0
0
0
59
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
75
0
0
0
0
67
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
17
0
0
0
0
0
9
0
0
0
67
% K
% Leu:
59
0
0
0
0
0
0
0
0
75
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% P
% Gln:
0
59
9
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
67
0
0
0
75
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _