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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKI
All Species:
18.79
Human Site:
S508
Identified Species:
45.93
UniProt:
P12755
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12755
NP_003027.1
728
80005
S508
S
P
S
F
T
S
S
S
S
A
K
D
L
G
S
Chimpanzee
Pan troglodytes
XP_001163333
684
77021
K544
T
Y
L
K
Q
Q
E
K
L
N
L
I
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001086434
970
105418
S498
S
P
S
F
T
S
S
S
S
A
K
D
L
G
S
Dog
Lupus familis
XP_546730
790
86467
S567
S
P
S
L
T
S
S
S
S
A
K
D
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60698
725
80101
S505
S
P
S
F
T
S
S
S
S
A
K
D
L
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517777
395
43609
V261
V
S
V
E
F
Q
L
V
G
S
S
T
G
V
S
Chicken
Gallus gallus
P49140
750
84264
S527
S
P
S
F
T
S
S
S
S
A
K
D
M
S
S
Frog
Xenopus laevis
Q02225
717
80721
T491
S
L
S
S
P
S
F
T
S
S
S
S
A
K
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120210
709
79498
N554
F
P
S
Y
E
S
G
N
N
Q
K
E
L
P
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797484
647
73064
R500
K
L
L
H
E
L
A
R
I
R
S
S
Q
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.8
68.6
86.4
N.A.
92.1
N.A.
N.A.
34
79.1
74.3
N.A.
N.A.
N.A.
32.1
N.A.
39.2
Protein Similarity:
100
55.2
70.6
87.4
N.A.
93.5
N.A.
N.A.
40.5
86.6
82.2
N.A.
N.A.
N.A.
47.7
N.A.
54.5
P-Site Identity:
100
6.6
100
86.6
N.A.
93.3
N.A.
N.A.
6.6
86.6
26.6
N.A.
N.A.
N.A.
33.3
N.A.
0
P-Site Similarity:
100
13.3
100
86.6
N.A.
93.3
N.A.
N.A.
13.3
93.3
40
N.A.
N.A.
N.A.
60
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
50
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% D
% Glu:
0
0
0
10
20
0
10
0
0
0
0
10
0
10
20
% E
% Phe:
10
0
0
40
10
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
10
0
0
0
10
20
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
10
0
0
10
0
0
0
10
0
0
60
0
0
10
10
% K
% Leu:
0
20
20
10
0
10
10
0
10
0
10
0
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% N
% Pro:
0
60
0
0
10
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
20
0
0
0
10
0
0
10
10
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% R
% Ser:
60
10
70
10
0
70
50
50
60
20
30
20
0
30
60
% S
% Thr:
10
0
0
0
50
0
0
10
0
0
0
10
0
0
0
% T
% Val:
10
0
10
0
0
0
0
10
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _