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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKI
All Species:
23.94
Human Site:
S586
Identified Species:
58.52
UniProt:
P12755
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12755
NP_003027.1
728
80005
S586
A
A
L
Q
A
K
R
S
L
H
Q
E
L
E
F
Chimpanzee
Pan troglodytes
XP_001163333
684
77021
I610
L
E
K
K
L
E
Q
I
M
K
Q
K
C
T
C
Rhesus Macaque
Macaca mulatta
XP_001086434
970
105418
S576
A
A
L
Q
A
K
R
S
L
H
Q
E
L
E
F
Dog
Lupus familis
XP_546730
790
86467
S648
A
A
L
Q
A
K
R
S
L
H
Q
E
L
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q60698
725
80101
T583
A
A
L
Q
A
K
R
T
L
H
Q
E
L
E
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517777
395
43609
S327
I
E
G
E
E
R
P
S
P
G
R
K
D
Y
G
Chicken
Gallus gallus
P49140
750
84264
S608
A
A
L
Q
A
K
R
S
L
H
Q
E
L
E
F
Frog
Xenopus laevis
Q02225
717
80721
S575
A
A
L
Q
A
K
R
S
L
Q
Q
E
L
E
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120210
709
79498
E625
E
V
P
Q
D
V
L
E
L
A
R
R
I
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797484
647
73064
R568
E
S
N
E
S
R
Q
R
L
K
R
D
L
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.8
68.6
86.4
N.A.
92.1
N.A.
N.A.
34
79.1
74.3
N.A.
N.A.
N.A.
32.1
N.A.
39.2
Protein Similarity:
100
55.2
70.6
87.4
N.A.
93.5
N.A.
N.A.
40.5
86.6
82.2
N.A.
N.A.
N.A.
47.7
N.A.
54.5
P-Site Identity:
100
6.6
100
100
N.A.
93.3
N.A.
N.A.
6.6
100
93.3
N.A.
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
100
40
100
100
N.A.
100
N.A.
N.A.
33.3
100
93.3
N.A.
N.A.
N.A.
26.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
60
0
0
60
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
10
10
0
0
% D
% Glu:
20
20
0
20
10
10
0
10
0
0
0
60
0
70
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
10
0
60
0
0
0
20
0
20
0
0
0
% K
% Leu:
10
0
60
0
10
0
10
0
80
0
0
0
70
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
10
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
70
0
0
20
0
0
10
70
0
0
0
0
% Q
% Arg:
0
0
0
0
0
20
60
10
0
0
30
10
0
0
0
% R
% Ser:
0
10
0
0
10
0
0
60
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% T
% Val:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _