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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKI
All Species:
15.45
Human Site:
T461
Identified Species:
37.78
UniProt:
P12755
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12755
NP_003027.1
728
80005
T461
K
R
K
L
T
V
D
T
P
G
A
P
E
T
L
Chimpanzee
Pan troglodytes
XP_001163333
684
77021
L497
S
E
S
A
T
C
N
L
V
R
D
I
N
K
V
Rhesus Macaque
Macaca mulatta
XP_001086434
970
105418
T451
K
R
K
L
T
V
D
T
P
G
A
P
E
T
L
Dog
Lupus familis
XP_546730
790
86467
T520
K
R
K
L
T
V
D
T
P
G
A
P
E
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60698
725
80101
T458
K
R
K
L
T
L
D
T
A
G
A
P
D
M
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517777
395
43609
P214
W
E
S
R
P
G
G
P
S
H
P
L
H
P
F
Chicken
Gallus gallus
P49140
750
84264
T480
K
R
K
H
A
A
E
T
P
A
V
P
E
P
V
Frog
Xenopus laevis
Q02225
717
80721
L444
K
R
R
P
T
A
E
L
P
I
V
P
E
A
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120210
709
79498
H507
Q
R
R
H
H
H
E
H
K
R
Y
N
Q
H
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797484
647
73064
R453
S
P
D
G
E
K
E
R
D
I
K
C
E
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.8
68.6
86.4
N.A.
92.1
N.A.
N.A.
34
79.1
74.3
N.A.
N.A.
N.A.
32.1
N.A.
39.2
Protein Similarity:
100
55.2
70.6
87.4
N.A.
93.5
N.A.
N.A.
40.5
86.6
82.2
N.A.
N.A.
N.A.
47.7
N.A.
54.5
P-Site Identity:
100
6.6
100
93.3
N.A.
73.3
N.A.
N.A.
0
46.6
40
N.A.
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
20
100
93.3
N.A.
86.6
N.A.
N.A.
0
60
53.3
N.A.
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
20
0
0
10
10
40
0
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
10
0
0
0
40
0
10
0
10
0
10
10
0
% D
% Glu:
0
20
0
0
10
0
40
0
0
0
0
0
60
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
10
0
10
10
0
0
40
0
0
0
0
0
% G
% His:
0
0
0
20
10
10
0
10
0
10
0
0
10
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
20
0
10
0
0
0
% I
% Lys:
60
0
50
0
0
10
0
0
10
0
10
0
0
10
0
% K
% Leu:
0
0
0
40
0
10
0
20
0
0
0
10
0
0
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
10
10
0
0
% N
% Pro:
0
10
0
10
10
0
0
10
50
0
10
60
0
20
20
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
70
20
10
0
0
0
10
0
20
0
0
0
0
0
% R
% Ser:
20
0
20
0
0
0
0
0
10
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
60
0
0
50
0
0
0
0
0
30
0
% T
% Val:
0
0
0
0
0
30
0
0
10
0
20
0
0
0
20
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _