KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKI
All Species:
17.88
Human Site:
Y406
Identified Species:
43.7
UniProt:
P12755
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12755
NP_003027.1
728
80005
Y406
A
L
I
R
D
S
F
Y
S
Y
K
S
F
E
T
Chimpanzee
Pan troglodytes
XP_001163333
684
77021
G445
S
E
K
A
H
S
S
G
K
L
Q
K
T
V
S
Rhesus Macaque
Macaca mulatta
XP_001086434
970
105418
Y396
A
L
I
R
D
S
F
Y
S
Y
K
S
F
E
T
Dog
Lupus familis
XP_546730
790
86467
Y465
A
L
I
R
D
S
F
Y
S
Y
K
S
F
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q60698
725
80101
Y403
A
L
I
R
D
S
F
Y
S
Y
K
S
F
E
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517777
395
43609
K162
D
Y
T
G
K
E
E
K
A
R
L
G
Q
C
L
Chicken
Gallus gallus
P49140
750
84264
F424
A
L
I
R
D
S
S
F
Y
S
Y
K
S
F
E
Frog
Xenopus laevis
Q02225
717
80721
Y389
A
L
I
R
D
S
F
Y
N
Y
K
S
F
E
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120210
709
79498
P454
A
Y
L
S
R
G
P
P
V
L
Q
H
P
E
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797484
647
73064
L399
S
R
G
M
P
T
Y
L
S
M
G
P
P
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.8
68.6
86.4
N.A.
92.1
N.A.
N.A.
34
79.1
74.3
N.A.
N.A.
N.A.
32.1
N.A.
39.2
Protein Similarity:
100
55.2
70.6
87.4
N.A.
93.5
N.A.
N.A.
40.5
86.6
82.2
N.A.
N.A.
N.A.
47.7
N.A.
54.5
P-Site Identity:
100
6.6
100
100
N.A.
100
N.A.
N.A.
0
40
86.6
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
N.A.
N.A.
6.6
46.6
93.3
N.A.
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
10
10
0
0
0
0
0
0
60
10
% E
% Phe:
0
0
0
0
0
0
50
10
0
0
0
0
50
10
0
% F
% Gly:
0
0
10
10
0
10
0
10
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
10
0
0
10
10
0
50
20
0
0
0
% K
% Leu:
0
60
10
0
0
0
0
10
0
20
10
0
0
0
20
% L
% Met:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
10
0
10
10
0
0
0
10
20
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
20
0
10
0
0
% Q
% Arg:
0
10
0
60
10
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
20
0
0
10
0
70
20
0
50
10
0
50
10
0
10
% S
% Thr:
0
0
10
0
0
10
0
0
0
0
0
0
10
0
40
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
20
0
0
0
0
10
50
10
50
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _