KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SKIL
All Species:
19.7
Human Site:
S420
Identified Species:
54.17
UniProt:
P12757
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12757
NP_001138569.1
684
77004
S420
V
S
L
T
S
A
V
S
Q
S
K
E
L
T
K
Chimpanzee
Pan troglodytes
XP_001163333
684
77021
S420
V
S
L
T
S
A
V
S
Q
S
K
E
L
T
K
Rhesus Macaque
Macaca mulatta
XP_001085298
382
42492
S179
S
R
L
D
G
S
I
S
N
N
S
T
S
K
R
Dog
Lupus familis
XP_545283
685
77426
S421
V
S
L
T
S
T
V
S
Q
T
K
E
V
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q60665
675
76340
S417
V
S
L
T
S
A
A
S
Q
S
K
E
A
T
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519846
562
62167
T359
K
E
K
F
S
V
K
T
P
K
R
A
Q
Y
K
Chicken
Gallus gallus
P49140
750
84264
S459
P
P
C
A
T
V
V
S
R
S
S
E
P
P
S
Frog
Xenopus laevis
Q02225
717
80721
I457
A
P
A
P
P
V
P
I
R
E
E
E
K
E
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120210
709
79498
S450
S
L
V
P
A
Y
L
S
R
G
P
P
V
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
52.1
91.5
N.A.
87.8
N.A.
N.A.
56.8
21
39.4
N.A.
N.A.
N.A.
24.5
N.A.
N.A.
Protein Similarity:
100
99.7
53.3
95.1
N.A.
92.8
N.A.
N.A.
67.8
41.2
56.4
N.A.
N.A.
N.A.
43.1
N.A.
N.A.
P-Site Identity:
100
100
13.3
80
N.A.
86.6
N.A.
N.A.
13.3
26.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
40
93.3
N.A.
86.6
N.A.
N.A.
26.6
40
20
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
12
12
34
12
0
0
0
0
12
12
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
0
0
0
0
0
12
12
67
0
12
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
0
% I
% Lys:
12
0
12
0
0
0
12
0
0
12
45
0
12
12
56
% K
% Leu:
0
12
56
0
0
0
12
0
0
0
0
0
23
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% N
% Pro:
12
23
0
23
12
0
12
0
12
0
12
12
12
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
45
0
0
0
12
0
12
% Q
% Arg:
0
12
0
0
0
0
0
0
34
0
12
0
0
0
12
% R
% Ser:
23
45
0
0
56
12
0
78
0
45
23
0
12
0
23
% S
% Thr:
0
0
0
45
12
12
0
12
0
12
0
12
0
45
0
% T
% Val:
45
0
12
0
0
34
45
0
0
0
0
0
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _