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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYL4
All Species:
28.79
Human Site:
T49
Identified Species:
52.78
UniProt:
P12829
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12829
NP_001002841.1
197
21565
T49
K
S
V
K
I
D
F
T
A
D
Q
I
E
E
F
Chimpanzee
Pan troglodytes
XP_511623
193
21196
T45
K
S
V
K
I
D
F
T
A
D
Q
I
E
E
F
Rhesus Macaque
Macaca mulatta
XP_001116001
195
21434
T47
K
S
V
K
I
D
F
T
A
D
Q
I
E
E
F
Dog
Lupus familis
XP_537609
191
21039
T43
K
S
V
K
I
D
F
T
A
D
Q
I
E
E
F
Cat
Felis silvestris
Mouse
Mus musculus
P09541
193
21141
S45
K
S
V
K
I
D
F
S
A
D
Q
I
E
E
F
Rat
Rattus norvegicus
P17209
193
21264
S45
K
S
V
K
I
D
F
S
A
D
Q
I
E
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510531
159
17712
A18
E
A
A
K
P
T
P
A
P
A
P
A
P
E
P
Chicken
Gallus gallus
P09540
185
20601
A37
K
S
V
K
I
E
F
A
A
E
Q
I
E
E
F
Frog
Xenopus laevis
NP_001079225
190
21167
A42
K
S
V
T
V
E
F
A
A
D
Q
I
E
E
F
Zebra Danio
Brachydanio rerio
XP_001921730
187
20941
T39
K
S
I
K
V
E
F
T
A
D
Q
I
E
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54357
147
16595
E14
D
Q
L
A
E
F
Q
E
A
F
N
L
F
D
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P53014
153
17126
Y16
L
K
E
I
F
N
L
Y
D
E
E
L
D
G
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P25069
149
16801
E15
D
Q
I
S
E
F
K
E
A
F
S
L
F
D
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
97.9
95.4
N.A.
90.8
89.8
N.A.
71.5
79.6
84.2
79.1
N.A.
41.6
N.A.
34.5
N.A.
Protein Similarity:
100
97.9
98.4
95.4
N.A.
93.4
92.3
N.A.
76.6
86.2
90.3
87.3
N.A.
55.8
N.A.
49.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
13.3
80
73.3
80
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
93.3
86.6
100
N.A.
26.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
0
0
24
85
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
47
0
0
8
62
0
0
8
16
0
% D
% Glu:
8
0
8
0
16
24
0
16
0
16
8
0
70
77
0
% E
% Phe:
0
0
0
0
8
16
70
0
0
16
0
0
16
0
70
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
8
54
0
0
0
0
0
0
70
0
0
0
% I
% Lys:
70
8
0
70
0
0
8
0
0
0
0
0
0
0
16
% K
% Leu:
8
0
8
0
0
0
8
0
0
0
0
24
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% N
% Pro:
0
0
0
0
8
0
8
0
8
0
8
0
8
0
8
% P
% Gln:
0
16
0
0
0
0
8
0
0
0
70
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
70
0
8
0
0
0
16
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
8
0
8
0
39
0
0
0
0
0
0
0
% T
% Val:
0
0
62
0
16
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _