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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLN
All Species:
15.15
Human Site:
S57
Identified Species:
55.56
UniProt:
P12872
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12872
NP_001035198.1
115
12920
S57
S
L
S
V
W
Q
R
S
G
E
E
G
P
V
D
Chimpanzee
Pan troglodytes
XP_001171525
115
12845
S57
S
L
S
V
W
Q
R
S
G
E
E
G
P
V
D
Rhesus Macaque
Macaca mulatta
O18811
115
12802
S57
S
L
S
V
W
Q
R
S
G
E
E
G
P
V
D
Dog
Lupus familis
XP_538869
129
14425
S57
S
L
I
L
Q
K
K
S
E
E
V
G
P
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001103526
48
5216
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510662
124
13766
S54
S
L
T
V
Q
Q
R
S
E
Q
G
G
L
R
T
Chicken
Gallus gallus
XP_001231330
115
12875
L57
S
L
T
P
L
Q
Q
L
E
E
D
D
F
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
93.9
67.4
N.A.
N.A.
29.5
N.A.
57.2
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
94.7
77.5
N.A.
N.A.
33
N.A.
69.3
62.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
46.6
N.A.
N.A.
0
N.A.
46.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
N.A.
0
N.A.
60
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
15
15
0
0
58
% D
% Glu:
0
0
0
0
0
0
0
0
43
72
43
0
0
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
43
0
15
72
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
15
15
0
0
0
0
0
0
0
0
% K
% Leu:
0
86
0
15
15
0
0
15
0
0
0
0
15
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
15
0
0
0
0
0
0
0
0
58
0
0
% P
% Gln:
0
0
0
0
29
72
15
0
0
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
58
0
0
0
0
0
0
15
0
% R
% Ser:
86
0
43
0
0
0
0
72
0
0
0
0
0
15
0
% S
% Thr:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
15
% T
% Val:
0
0
0
58
0
0
0
0
0
0
15
0
0
43
0
% V
% Trp:
0
0
0
0
43
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _