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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRC
All Species:
31.82
Human Site:
S219
Identified Species:
70
UniProt:
P12931
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12931
NP_005408.1
536
59835
S219
S
G
G
F
Y
I
T
S
R
T
Q
F
N
S
L
Chimpanzee
Pan troglodytes
XP_001140981
532
58910
K219
C
V
G
G
T
W
T
K
T
R
L
T
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001092180
536
59788
S219
S
G
G
F
Y
I
T
S
R
T
Q
F
N
S
L
Dog
Lupus familis
XP_865870
536
59880
S219
S
G
G
F
Y
I
T
S
R
T
Q
F
N
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P05480
541
60600
S224
S
G
G
F
Y
I
T
S
R
T
Q
F
N
S
L
Rat
Rattus norvegicus
Q9WUD9
536
60060
S219
S
G
G
F
Y
I
T
S
R
T
Q
F
N
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508295
452
51612
Q170
V
C
P
T
V
K
P
Q
T
Q
G
L
A
K
D
Chicken
Gallus gallus
P00523
533
59991
S216
S
G
G
F
Y
I
T
S
R
T
Q
F
S
S
L
Frog
Xenopus laevis
P13116
532
59718
S215
S
G
G
F
Y
I
T
S
R
T
Q
F
S
S
L
Zebra Danio
Brachydanio rerio
NP_001003837
534
60119
S217
S
G
G
F
Y
I
T
S
R
T
Q
F
S
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9J3
517
59051
L218
S
D
G
L
C
V
N
L
C
K
P
C
V
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.7
99.8
98.8
N.A.
97.7
98.5
N.A.
70.9
94.4
87.6
83.2
N.A.
54
N.A.
N.A.
N.A.
Protein Similarity:
100
95.3
99.8
98.8
N.A.
98.3
99.2
N.A.
78.7
96.2
92.1
88.8
N.A.
67.1
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
0
93.3
93.3
86.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% A
% Cys:
10
10
0
0
10
0
0
0
10
0
0
10
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
73
0
0
0
0
0
0
0
73
0
0
0
% F
% Gly:
0
73
91
10
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
73
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
10
0
10
0
10
0
0
0
10
0
% K
% Leu:
0
0
0
10
0
0
0
10
0
0
10
10
0
0
73
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
46
0
0
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
10
0
0
10
10
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
73
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
73
10
0
0
0
0
0
% R
% Ser:
82
0
0
0
0
0
0
73
0
0
0
0
28
64
0
% S
% Thr:
0
0
0
10
10
0
82
0
19
73
0
10
0
10
0
% T
% Val:
10
10
0
0
10
10
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
73
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _