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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEPD All Species: 29.39
Human Site: S103 Identified Species: 46.19
UniProt: P12955 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12955 NP_000276.2 493 54548 S103 F V P R L P A S H A T W M G K
Chimpanzee Pan troglodytes XP_512574 512 55464 A118 G A C R A G P A S R R L V P R
Rhesus Macaque Macaca mulatta XP_001108576 530 56754 G115 Q A L A Q S S G P N V R G L H
Dog Lupus familis XP_533702 493 54844 S103 F V P R L P A S Y A T W M G K
Cat Felis silvestris
Mouse Mus musculus Q11136 493 55010 S103 F V P R L P D S Y A T W M G K
Rat Rattus norvegicus Q5I0D7 492 54732 S103 F V P R L P A S Y A T W M G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509666 502 56104 S114 F V P K L P E S H A T W M G K
Chicken Gallus gallus NP_001073185 497 55164 S103 F V P L L P E S Y A V W M G K
Frog Xenopus laevis NP_001079825 498 55276 S103 F I P K L P E S Y A V W M G K
Zebra Danio Brachydanio rerio NP_944594 496 55257 S104 F V P K L P E S Y A T W M G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_490843 498 55663 I100 R L D P S Y A I W D G K I N N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002308288 488 54388 D100 F A P R L P A D Y A V W L G E
Maize Zea mays NP_001150104 509 56681 D102 F A P R L P A D Y A V W M G E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194678 486 54383 D97 F I P R L P D D Y A V W L G E
Baker's Yeast Sacchar. cerevisiae P43590 535 61735 E104 T A F F I A G E E L E G N K Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.9 53.4 92.6 N.A. 89 89 N.A. 79.6 78.4 75.6 73.1 N.A. N.A. N.A. 52.8 N.A.
Protein Similarity: 100 66.4 61.3 96.9 N.A. 94.1 94.3 N.A. 87.6 89.5 88.9 84.6 N.A. N.A. N.A. 67.4 N.A.
P-Site Identity: 100 6.6 0 93.3 N.A. 86.6 93.3 N.A. 86.6 73.3 66.6 73.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 26.6 6.6 100 N.A. 93.3 100 N.A. 93.3 80 86.6 93.3 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: 55.9 51 N.A. 54.9 27.4 N.A.
Protein Similarity: 69.3 64.6 N.A. 68.7 43.1 N.A.
P-Site Identity: 60 66.6 N.A. 53.3 0 N.A.
P-Site Similarity: 80 80 N.A. 80 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 0 7 7 7 40 7 0 74 0 0 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 14 20 0 7 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 27 7 7 0 7 0 0 0 27 % E
% Phe: 74 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 7 7 7 0 0 7 7 7 74 0 % G
% His: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 7 % H
% Ile: 0 14 0 0 7 0 0 7 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 20 0 0 0 0 0 0 0 7 0 7 47 % K
% Leu: 0 7 7 7 74 0 0 0 0 7 0 7 14 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 0 7 7 7 % N
% Pro: 0 0 74 7 0 74 7 0 7 0 0 0 0 7 0 % P
% Gln: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 54 0 0 0 0 0 7 7 7 0 0 7 % R
% Ser: 0 0 0 0 7 7 7 54 7 0 0 0 0 0 0 % S
% Thr: 7 0 0 0 0 0 0 0 0 0 40 0 0 0 0 % T
% Val: 0 47 0 0 0 0 0 0 0 0 40 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 74 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 60 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _