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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEPD
All Species:
35.45
Human Site:
Y197
Identified Species:
55.71
UniProt:
P12955
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12955
NP_000276.2
493
54548
Y197
M
E
L
E
V
L
R
Y
T
N
K
I
S
S
E
Chimpanzee
Pan troglodytes
XP_512574
512
55464
Q212
G
C
A
L
L
G
P
Q
L
L
R
H
S
T
L
Rhesus Macaque
Macaca mulatta
XP_001108576
530
56754
K209
S
P
V
W
T
F
S
K
A
G
L
E
R
A
G
Dog
Lupus familis
XP_533702
493
54844
Y197
M
E
L
E
V
L
R
Y
T
N
R
I
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q11136
493
55010
Y197
M
E
L
E
V
L
R
Y
T
N
R
I
S
S
E
Rat
Rattus norvegicus
Q5I0D7
492
54732
Y197
M
E
L
E
V
L
R
Y
T
N
R
I
S
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509666
502
56104
Y208
M
E
L
E
V
L
R
Y
T
N
K
I
S
S
E
Chicken
Gallus gallus
NP_001073185
497
55164
Y197
M
E
L
E
V
L
R
Y
T
N
K
I
S
S
E
Frog
Xenopus laevis
NP_001079825
498
55276
Y197
M
E
L
E
V
L
R
Y
T
N
R
I
S
S
E
Zebra Danio
Brachydanio rerio
NP_944594
496
55257
Y198
M
E
L
E
V
L
R
Y
T
N
R
I
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490843
498
55663
Y194
K
E
I
G
V
M
R
Y
A
S
K
I
A
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002308288
488
54388
A194
L
K
S
D
M
E
L
A
L
I
Q
F
A
N
D
Maize
Zea mays
NP_001150104
509
56681
A196
I
K
S
D
L
E
L
A
L
I
R
Y
A
N
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194678
486
54383
Q191
I
K
S
S
L
E
L
Q
L
I
Q
F
A
N
D
Baker's Yeast
Sacchar. cerevisiae
P43590
535
61735
F198
E
L
Q
D
F
A
I
F
T
T
D
L
D
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.9
53.4
92.6
N.A.
89
89
N.A.
79.6
78.4
75.6
73.1
N.A.
N.A.
N.A.
52.8
N.A.
Protein Similarity:
100
66.4
61.3
96.9
N.A.
94.1
94.3
N.A.
87.6
89.5
88.9
84.6
N.A.
N.A.
N.A.
67.4
N.A.
P-Site Identity:
100
6.6
0
93.3
N.A.
93.3
93.3
N.A.
100
100
93.3
93.3
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
100
26.6
13.3
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
55.9
51
N.A.
54.9
27.4
N.A.
Protein Similarity:
69.3
64.6
N.A.
68.7
43.1
N.A.
P-Site Identity:
0
0
N.A.
0
6.6
N.A.
P-Site Similarity:
53.3
53.3
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
14
14
0
0
0
27
7
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
0
0
7
0
7
0
20
% D
% Glu:
7
60
0
54
0
20
0
0
0
0
0
7
0
0
60
% E
% Phe:
0
0
0
0
7
7
0
7
0
0
0
14
0
0
0
% F
% Gly:
7
0
0
7
0
7
0
0
0
7
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
14
0
7
0
0
0
7
0
0
20
0
60
0
0
0
% I
% Lys:
7
20
0
0
0
0
0
7
0
0
27
0
0
0
0
% K
% Leu:
7
7
54
7
20
54
20
0
27
7
7
7
0
0
7
% L
% Met:
54
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
54
0
0
0
27
0
% N
% Pro:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
14
0
0
14
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
60
0
0
0
47
0
7
0
0
% R
% Ser:
7
0
20
7
0
0
7
0
0
7
0
0
60
60
0
% S
% Thr:
0
0
0
0
7
0
0
0
60
7
0
0
0
7
0
% T
% Val:
0
0
7
0
60
0
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _