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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
18.79
Human Site:
S180
Identified Species:
29.52
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
S180
D
N
P
H
G
N
D
S
A
K
A
S
R
A
R
Chimpanzee
Pan troglodytes
XP_521301
565
64749
H157
G
I
F
L
D
L
M
H
L
K
K
P
G
G
F
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
P158
D
L
M
H
L
K
K
P
G
G
F
D
I
S
L
Dog
Lupus familis
XP_531714
608
69589
S178
D
D
P
H
G
N
D
S
A
K
A
S
R
A
R
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
S178
D
D
P
H
G
R
D
S
A
K
A
S
R
A
R
Rat
Rattus norvegicus
NP_620780
608
69468
S178
D
D
P
H
G
N
D
S
A
K
A
S
R
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
D29
D
I
I
N
T
A
E
D
E
D
L
G
V
H
F
Chicken
Gallus gallus
O93257
632
72271
S202
D
N
P
H
A
N
D
S
A
K
A
K
L
A
R
Frog
Xenopus laevis
NP_001082274
611
69251
P178
D
N
P
H
A
N
D
P
A
K
A
K
Q
A
R
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
D25
D
E
E
E
S
G
G
D
Y
K
S
S
G
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
S181
R
E
P
H
P
S
N
S
N
H
F
Q
A
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
V178
D
H
P
H
D
K
N
V
A
F
Q
R
Q
A
K
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
K184
D
D
P
F
G
S
I
K
G
V
A
K
A
D
M
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
R185
D
D
P
F
G
S
M
R
I
S
V
K
E
D
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
K185
D
D
P
H
A
G
D
K
Q
A
K
S
S
A
A
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
6.6
13.3
93.3
N.A.
86.6
93.3
N.A.
6.6
80
73.3
20
N.A.
26.6
N.A.
N.A.
33.3
P-Site Similarity:
100
6.6
20
100
N.A.
93.3
100
N.A.
20
80
80
26.6
N.A.
40
N.A.
N.A.
60
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
26.6
N.A.
N.A.
20
N.A.
40
P-Site Similarity:
40
N.A.
N.A.
33.3
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
7
0
0
47
7
47
0
14
60
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
87
40
0
0
14
0
47
14
0
7
0
7
0
14
7
% D
% Glu:
0
14
7
7
0
0
7
0
7
0
0
0
7
0
0
% E
% Phe:
0
0
7
14
0
0
0
0
0
7
14
0
0
0
14
% F
% Gly:
7
0
0
0
40
14
7
0
14
7
0
7
14
7
0
% G
% His:
0
7
0
67
0
0
0
7
0
7
0
0
0
7
0
% H
% Ile:
0
14
7
0
0
0
7
0
7
0
0
0
7
0
0
% I
% Lys:
0
0
0
0
0
14
7
14
0
54
14
27
0
0
7
% K
% Leu:
0
7
0
7
7
7
0
0
7
0
7
0
7
0
14
% L
% Met:
0
0
7
0
0
0
14
0
0
0
0
0
0
0
14
% M
% Asn:
0
20
0
7
0
34
14
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
74
0
7
0
0
14
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
7
7
14
0
0
% Q
% Arg:
7
0
0
0
0
7
0
7
0
0
0
7
27
7
40
% R
% Ser:
0
0
0
0
7
20
0
40
0
7
7
40
7
7
0
% S
% Thr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
7
0
7
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _