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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
15.76
Human Site:
S257
Identified Species:
24.76
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
S257
E
T
R
K
R
A
L
S
R
L
K
L
K
L
N
Chimpanzee
Pan troglodytes
XP_521301
565
64749
K232
G
I
Y
N
L
V
Q
K
A
L
K
P
P
P
I
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
K232
N
L
V
Q
K
A
L
K
P
P
P
I
K
L
Y
Dog
Lupus familis
XP_531714
608
69589
C255
E
T
R
K
R
V
L
C
R
L
K
L
K
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
S255
E
T
K
K
R
V
L
S
R
L
K
F
K
L
G
Rat
Rattus norvegicus
NP_620780
608
69468
S255
E
T
K
K
R
V
L
S
R
L
K
F
K
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
T103
N
E
P
V
K
T
K
T
R
T
F
N
L
D
T
Chicken
Gallus gallus
O93257
632
72271
S279
E
T
R
K
R
A
L
S
R
L
N
L
Y
L
N
Frog
Xenopus laevis
NP_001082274
611
69251
S255
E
A
K
K
R
A
L
S
R
L
N
L
K
L
G
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
V99
P
R
N
S
F
K
H
V
Y
V
Y
H
D
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
G258
D
F
L
R
R
C
L
G
H
F
S
F
Y
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
G255
D
H
K
K
R
T
T
G
R
I
P
F
S
L
G
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
R267
M
F
T
K
R
I
V
R
R
I
T
L
S
I
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
K268
V
L
A
K
R
I
A
K
R
I
T
F
V
I
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
R268
N
S
K
Q
T
P
K
R
S
Y
F
S
N
L
P
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
13.3
26.6
80
N.A.
73.3
73.3
N.A.
6.6
86.6
73.3
6.6
N.A.
20
N.A.
N.A.
26.6
P-Site Similarity:
100
13.3
46.6
86.6
N.A.
80
80
N.A.
20
86.6
80
13.3
N.A.
33.3
N.A.
N.A.
46.6
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
26.6
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
46.6
N.A.
N.A.
33.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
27
7
0
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
7
% C
% Asp:
14
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% D
% Glu:
40
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
14
0
0
7
0
0
0
0
7
14
34
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
14
0
0
0
0
0
0
34
% G
% His:
0
7
0
0
0
0
7
0
7
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
0
14
0
0
0
20
0
7
0
14
7
% I
% Lys:
0
0
34
60
14
7
14
20
0
0
34
0
40
0
0
% K
% Leu:
0
14
7
0
7
0
54
0
0
47
0
34
7
74
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
7
7
0
0
0
0
0
0
14
7
7
0
14
% N
% Pro:
7
0
7
0
0
7
0
0
7
7
14
7
7
7
7
% P
% Gln:
0
0
0
14
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
20
7
67
0
0
14
67
0
0
0
0
0
0
% R
% Ser:
0
7
0
7
0
0
0
34
7
0
7
7
14
0
7
% S
% Thr:
0
34
7
0
7
14
7
7
0
7
14
0
0
0
7
% T
% Val:
7
0
7
7
0
27
7
7
0
7
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
7
7
7
0
14
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _