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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
0.61
Human Site:
S306
Identified Species:
0.95
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
S306
K
T
R
T
F
N
T
S
T
G
G
L
L
L
P
Chimpanzee
Pan troglodytes
XP_521301
565
64749
I281
I
Y
G
S
R
Q
I
I
L
E
K
E
E
T
E
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
K281
S
R
Q
I
I
L
E
K
E
E
T
E
E
L
K
Dog
Lupus familis
XP_531714
608
69589
N304
K
T
R
T
F
N
V
N
T
G
S
L
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
N304
K
T
R
T
F
N
V
N
T
G
S
L
L
L
P
Rat
Rattus norvegicus
NP_620780
608
69468
N304
K
T
R
T
F
N
V
N
T
G
S
L
L
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
G152
D
P
G
L
I
L
I
G
F
K
P
L
T
T
L
Chicken
Gallus gallus
O93257
632
72271
K328
K
T
R
V
F
N
G
K
T
G
S
L
L
L
P
Frog
Xenopus laevis
NP_001082274
611
69251
N304
K
T
R
I
F
H
S
N
T
G
S
L
L
L
P
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
N148
E
A
L
W
C
C
S
N
L
Y
S
D
I
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
K307
K
R
V
I
T
V
Q
K
Q
K
D
D
G
S
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
D304
K
S
K
M
Y
C
E
D
T
G
E
L
L
M
P
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
D316
E
R
S
F
I
C
A
D
T
G
A
L
M
Q
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
D317
E
R
S
Y
I
C
T
D
T
G
A
I
M
Q
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
T317
A
Q
V
V
Q
S
E
T
A
Q
V
D
F
A
A
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
0
6.6
80
N.A.
80
80
N.A.
6.6
73.3
66.6
0
N.A.
6.6
N.A.
N.A.
40
P-Site Similarity:
100
6.6
13.3
86.6
N.A.
86.6
86.6
N.A.
6.6
73.3
86.6
26.6
N.A.
6.6
N.A.
N.A.
66.6
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
20
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
33.3
N.A.
N.A.
40
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
7
0
7
0
14
0
0
7
7
% A
% Cys:
0
0
0
0
7
27
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
20
0
0
7
20
0
0
7
% D
% Glu:
20
0
0
0
0
0
20
0
7
14
7
14
14
0
14
% E
% Phe:
0
0
0
7
40
0
0
0
7
0
0
0
7
0
0
% F
% Gly:
0
0
14
0
0
0
7
7
0
60
7
0
7
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
20
27
0
14
7
0
0
0
7
7
0
0
% I
% Lys:
54
0
7
0
0
0
0
20
0
14
7
0
0
7
7
% K
% Leu:
0
0
7
7
0
14
0
0
14
0
0
60
47
47
14
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
14
7
0
% M
% Asn:
0
0
0
0
0
34
0
34
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
47
% P
% Gln:
0
7
7
0
7
7
7
0
7
7
0
0
0
14
7
% Q
% Arg:
0
27
40
0
7
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
7
14
7
0
7
14
7
0
0
40
0
0
7
0
% S
% Thr:
0
40
0
27
7
0
14
7
60
0
7
0
7
14
0
% T
% Val:
0
0
14
14
0
7
20
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
7
7
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _