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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC6 All Species: 13.33
Human Site: S33 Identified Species: 20.95
UniProt: P12956 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12956 NP_001460.1 609 69843 S33 A S G D Y K Y S G R D S L I F
Chimpanzee Pan troglodytes XP_521301 565 64749 S31 Y I S K I I S S D R D L L A V
Rhesus Macaque Macaca mulatta XP_001105684 559 64235 L32 I I S S D R D L L A V V F Y G
Dog Lupus familis XP_531714 608 69589 S31 A G G E Y T Y S G R D S L I F
Cat Felis silvestris
Mouse Mus musculus P23475 608 69466 S31 T G G E Y K Y S G R D S L I F
Rat Rattus norvegicus NP_620780 608 69468 S31 T N G E Y K Y S G R D S L I F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507917 413 47433
Chicken Gallus gallus O93257 632 72271 G55 V A D Y R F S G R D S L I F L
Frog Xenopus laevis NP_001082274 611 69251 F31 S D A S A F R F S G R D S L I
Zebra Danio Brachydanio rerio NP_956198 409 46098
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q23976 631 72517 A33 R D Y H G R E A I L F V V D A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189673 580 65781 K32 E Y G G A E W K N A G K D S L
Poplar Tree Populus trichocarpa XP_002317447 628 70376 G51 S T C P S E D G K E E T H F H
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564012 621 70272 V31 K E A S K E F V V Y L I D A S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SA95 645 72334 L33 K T Q K D A V L F A I D V S K
Conservation
Percent
Protein Identity: 100 88 89.8 84.7 N.A. 83.2 83.2 N.A. 53.6 68 65.6 39 N.A. 25 N.A. N.A. 45.6
Protein Similarity: 100 89.3 91.1 92.9 N.A. 90.9 91.7 N.A. 59.9 81.9 81.1 53.2 N.A. 45.9 N.A. N.A. 64.8
P-Site Identity: 100 26.6 0 80 N.A. 80 80 N.A. 0 0 0 0 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 26.6 6.6 86.6 N.A. 86.6 93.3 N.A. 0 13.3 13.3 0 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: 30.7 N.A. N.A. 30.2 N.A. 27.6
Protein Similarity: 50 N.A. N.A. 48.6 N.A. 48.5
P-Site Identity: 0 N.A. N.A. 0 N.A. 0
P-Site Similarity: 33.3 N.A. N.A. 13.3 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 14 0 14 7 0 7 0 20 0 0 0 14 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 7 7 14 0 14 0 7 7 34 14 14 7 0 % D
% Glu: 7 7 0 20 0 20 7 0 0 7 7 0 0 0 0 % E
% Phe: 0 0 0 0 0 14 7 7 7 0 7 0 7 14 27 % F
% Gly: 0 14 34 7 7 0 0 14 27 7 7 0 0 0 7 % G
% His: 0 0 0 7 0 0 0 0 0 0 0 0 7 0 7 % H
% Ile: 7 14 0 0 7 7 0 0 7 0 7 7 7 27 7 % I
% Lys: 14 0 0 14 7 20 0 7 7 0 0 7 0 0 7 % K
% Leu: 0 0 0 0 0 0 0 14 7 7 7 14 34 7 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 7 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 7 14 7 0 7 34 7 0 0 0 0 % R
% Ser: 14 7 14 20 7 0 14 34 7 0 7 27 7 14 7 % S
% Thr: 14 14 0 0 0 7 0 0 0 0 0 7 0 0 0 % T
% Val: 7 0 0 0 0 0 7 7 7 0 7 14 14 0 7 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 7 7 27 0 27 0 0 7 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _