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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC6 All Species: 9.39
Human Site: T10 Identified Species: 14.76
UniProt: P12956 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12956 NP_001460.1 609 69843 T10 G W E S Y Y K T E G D E E A E
Chimpanzee Pan troglodytes XP_521301 565 64749 L10 E S Q S E D E L T P F D M S I
Rhesus Macaque Macaca mulatta XP_001105684 559 64235 T11 Q K K N K K R T L K Q V C I Q
Dog Lupus familis XP_531714 608 69589 N10 G W E S Y Y K N E G D E E G E
Cat Felis silvestris
Mouse Mus musculus P23475 608 69466 T10 E W E S Y Y K T E G E E E E E
Rat Rattus norvegicus NP_620780 608 69468 T10 E W E S Y Y K T E G E E E E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507917 413 47433
Chicken Gallus gallus O93257 632 72271 G28 D W V S Y Y R G D G P D E E E
Frog Xenopus laevis NP_001082274 611 69251 N10 E W G D H F V N Q E V E D D E
Zebra Danio Brachydanio rerio NP_956198 409 46098
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q23976 631 72517 V10 T W N P E N D V D L L S G S E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189673 580 65781 F10 N W G G N S G F G Y Y D A G D
Poplar Tree Populus trichocarpa XP_002317447 628 70376 D12 P D D I F K D D E D D P D S E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564012 621 70272 R10 L D P D D V F R D E D E D P E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SA95 645 72334 R10 W R K D Q D E R L D G D E G D
Conservation
Percent
Protein Identity: 100 88 89.8 84.7 N.A. 83.2 83.2 N.A. 53.6 68 65.6 39 N.A. 25 N.A. N.A. 45.6
Protein Similarity: 100 89.3 91.1 92.9 N.A. 90.9 91.7 N.A. 59.9 81.9 81.1 53.2 N.A. 45.9 N.A. N.A. 64.8
P-Site Identity: 100 6.6 6.6 86.6 N.A. 80 80 N.A. 0 46.6 20 0 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 33.3 33.3 86.6 N.A. 86.6 86.6 N.A. 0 66.6 46.6 0 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: 30.7 N.A. N.A. 30.2 N.A. 27.6
Protein Similarity: 50 N.A. N.A. 48.6 N.A. 48.5
P-Site Identity: 20 N.A. N.A. 20 N.A. 6.6
P-Site Similarity: 46.6 N.A. N.A. 33.3 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 7 14 7 20 7 14 14 7 20 14 27 27 20 7 14 % D
% Glu: 27 0 27 0 14 0 14 0 34 14 14 40 40 20 60 % E
% Phe: 0 0 0 0 7 7 7 7 0 0 7 0 0 0 0 % F
% Gly: 14 0 14 7 0 0 7 7 7 34 7 0 7 20 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 7 % I
% Lys: 0 7 14 0 7 14 27 0 0 7 0 0 0 0 0 % K
% Leu: 7 0 0 0 0 0 0 7 14 7 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 7 0 7 7 7 7 0 14 0 0 0 0 0 0 0 % N
% Pro: 7 0 7 7 0 0 0 0 0 7 7 7 0 7 0 % P
% Gln: 7 0 7 0 7 0 0 0 7 0 7 0 0 0 7 % Q
% Arg: 0 7 0 0 0 0 14 14 0 0 0 0 0 0 0 % R
% Ser: 0 7 0 40 0 7 0 0 0 0 0 7 0 20 0 % S
% Thr: 7 0 0 0 0 0 0 27 7 0 0 0 0 0 0 % T
% Val: 0 0 7 0 0 7 7 7 0 0 7 7 0 0 0 % V
% Trp: 7 54 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 34 34 0 0 0 7 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _