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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC6 All Species: 33.03
Human Site: T292 Identified Species: 51.9
UniProt: P12956 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12956 NP_001460.1 609 69843 T292 P I K L Y R E T N E P V K T K
Chimpanzee Pan troglodytes XP_521301 565 64749 S267 T G G L L L P S D T K R S Q I
Rhesus Macaque Macaca mulatta XP_001105684 559 64235 K267 L L L P S D T K R S Q I Y G S
Dog Lupus familis XP_531714 608 69589 T290 P V R L Y R E T N E P V K S K
Cat Felis silvestris
Mouse Mus musculus P23475 608 69466 T290 P V R L Y R E T N E P V K T K
Rat Rattus norvegicus NP_620780 608 69468 T290 P V R L Y R E T N E P V K T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507917 413 47433 E138 V M E K E E T E E L K R F D D
Chicken Gallus gallus O93257 632 72271 T314 P V K L Y R E T N E P V K T K
Frog Xenopus laevis NP_001082274 611 69251 S290 T V R L Y R E S N E P V K T K
Zebra Danio Brachydanio rerio NP_956198 409 46098 S134 F A E K T M G S G E T S L G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q23976 631 72517 D293 K V Q I L R R D N S V V R T K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189673 580 65781 T290 P V K L H R Q T N E A L K N K
Poplar Tree Populus trichocarpa XP_002317447 628 70376 S302 I T W L D S V S N R P L K T E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564012 621 70272 T303 I T W L D S T T N L P V K V E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SA95 645 72334 V303 T P T R S C Y V Y E G E E Q A
Conservation
Percent
Protein Identity: 100 88 89.8 84.7 N.A. 83.2 83.2 N.A. 53.6 68 65.6 39 N.A. 25 N.A. N.A. 45.6
Protein Similarity: 100 89.3 91.1 92.9 N.A. 90.9 91.7 N.A. 59.9 81.9 81.1 53.2 N.A. 45.9 N.A. N.A. 64.8
P-Site Identity: 100 6.6 0 80 N.A. 86.6 86.6 N.A. 0 93.3 73.3 6.6 N.A. 33.3 N.A. N.A. 60
P-Site Similarity: 100 20 13.3 100 N.A. 100 100 N.A. 13.3 100 93.3 26.6 N.A. 60 N.A. N.A. 86.6
Percent
Protein Identity: 30.7 N.A. N.A. 30.2 N.A. 27.6
Protein Similarity: 50 N.A. N.A. 48.6 N.A. 48.5
P-Site Identity: 33.3 N.A. N.A. 40 N.A. 6.6
P-Site Similarity: 53.3 N.A. N.A. 46.6 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 14 7 0 7 7 0 0 0 0 7 7 % D
% Glu: 0 0 14 0 7 7 40 7 7 60 0 7 7 0 20 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 7 7 0 0 0 7 0 7 0 7 0 0 14 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 7 0 7 0 0 0 0 0 0 0 7 0 0 7 % I
% Lys: 7 0 20 14 0 0 0 7 0 0 14 0 60 0 54 % K
% Leu: 7 7 7 67 14 7 0 0 0 14 0 14 7 0 0 % L
% Met: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 67 0 0 0 0 7 0 % N
% Pro: 40 7 0 7 0 0 7 0 0 0 54 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 7 0 0 0 7 0 0 14 0 % Q
% Arg: 0 0 27 7 0 54 7 0 7 7 0 14 7 0 0 % R
% Ser: 0 0 0 0 14 14 0 27 0 14 0 7 7 7 7 % S
% Thr: 20 14 7 0 7 0 20 47 0 7 7 0 0 47 0 % T
% Val: 7 47 0 0 0 0 7 7 0 0 7 54 0 7 0 % V
% Trp: 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 40 0 7 0 7 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _