Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC6 All Species: 20.3
Human Site: T316 Identified Species: 31.9
UniProt: P12956 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12956 NP_001460.1 609 69843 T316 G L L L P S D T K R S Q I Y G
Chimpanzee Pan troglodytes XP_521301 565 64749 K291 K E E T E E L K R F D D P G L
Rhesus Macaque Macaca mulatta XP_001105684 559 64235 D291 T E E L K R F D D P G L M L M
Dog Lupus familis XP_531714 608 69589 T314 S L L L P S D T K R S Q N Y G
Cat Felis silvestris
Mouse Mus musculus P23475 608 69466 T314 S L L L P S D T K R S L T Y G
Rat Rattus norvegicus NP_620780 608 69468 T314 S L L L P S D T K R S L T F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507917 413 47433 H162 P L T T L K R H Q Y L R P S Q
Chicken Gallus gallus O93257 632 72271 T338 S L L L P S D T K R A Q T Y G
Frog Xenopus laevis NP_001082274 611 69251 T314 S L L L P S D T K R S Q T Y G
Zebra Danio Brachydanio rerio NP_956198 409 46098 S158 S D I K L R L S H K R L M I F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q23976 631 72517 E317 D D G S Q D I E H E Y Q I K V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189673 580 65781 I314 E L L M P S D I K K Y Q T Y G
Poplar Tree Populus trichocarpa XP_002317447 628 70376 K326 A L M Q E P A K R Y Q P Y K N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564012 621 70272 Q327 A I M Q D P I Q R I Q P Y K N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SA95 645 72334 V327 V D F A A R T V E K S E L R K
Conservation
Percent
Protein Identity: 100 88 89.8 84.7 N.A. 83.2 83.2 N.A. 53.6 68 65.6 39 N.A. 25 N.A. N.A. 45.6
Protein Similarity: 100 89.3 91.1 92.9 N.A. 90.9 91.7 N.A. 59.9 81.9 81.1 53.2 N.A. 45.9 N.A. N.A. 64.8
P-Site Identity: 100 0 6.6 86.6 N.A. 80 73.3 N.A. 6.6 80 86.6 0 N.A. 13.3 N.A. N.A. 60
P-Site Similarity: 100 6.6 13.3 86.6 N.A. 80 80 N.A. 20 86.6 86.6 26.6 N.A. 13.3 N.A. N.A. 73.3
Percent
Protein Identity: 30.7 N.A. N.A. 30.2 N.A. 27.6
Protein Similarity: 50 N.A. N.A. 48.6 N.A. 48.5
P-Site Identity: 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 20 N.A. N.A. 20 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 7 7 0 7 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 20 0 0 7 7 47 7 7 0 7 7 0 0 0 % D
% Glu: 7 14 14 0 14 7 0 7 7 7 0 7 0 0 0 % E
% Phe: 0 0 7 0 0 0 7 0 0 7 0 0 0 7 7 % F
% Gly: 7 0 7 0 0 0 0 0 0 0 7 0 0 7 47 % G
% His: 0 0 0 0 0 0 0 7 14 0 0 0 0 0 0 % H
% Ile: 0 7 7 0 0 0 14 7 0 7 0 0 14 7 0 % I
% Lys: 7 0 0 7 7 7 0 14 47 20 0 0 0 20 7 % K
% Leu: 0 60 47 47 14 0 14 0 0 0 7 27 7 7 7 % L
% Met: 0 0 14 7 0 0 0 0 0 0 0 0 14 0 7 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 14 % N
% Pro: 7 0 0 0 47 14 0 0 0 7 0 14 14 0 0 % P
% Gln: 0 0 0 14 7 0 0 7 7 0 14 40 0 0 7 % Q
% Arg: 0 0 0 0 0 20 7 0 20 40 7 7 0 7 0 % R
% Ser: 40 0 0 7 0 47 0 7 0 0 40 0 0 7 0 % S
% Thr: 7 0 7 14 0 0 7 40 0 0 0 0 34 0 0 % T
% Val: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 14 14 0 14 40 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _