KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC6
All Species:
30.3
Human Site:
Y534
Identified Species:
47.62
UniProt:
P12956
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12956
NP_001460.1
609
69843
Y534
E
L
V
Y
P
P
D
Y
N
P
E
G
K
V
T
Chimpanzee
Pan troglodytes
XP_521301
565
64749
Y490
E
L
V
Y
P
P
D
Y
N
P
E
G
K
V
T
Rhesus Macaque
Macaca mulatta
XP_001105684
559
64235
Y484
E
L
V
Y
P
P
D
Y
N
P
E
G
K
V
T
Dog
Lupus familis
XP_531714
608
69589
Y532
E
L
V
Y
P
P
D
Y
S
P
E
G
K
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P23475
608
69466
Y532
E
L
V
Y
P
P
G
Y
N
P
E
G
K
V
A
Rat
Rattus norvegicus
NP_620780
608
69468
Y532
E
L
V
Y
P
P
G
Y
N
P
E
G
K
I
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507917
413
47433
P339
V
Y
P
P
N
Y
N
P
E
G
K
A
V
K
R
Chicken
Gallus gallus
O93257
632
72271
Y556
Q
L
V
Y
P
P
D
Y
S
P
E
G
K
A
A
Frog
Xenopus laevis
NP_001082274
611
69251
Y532
E
L
V
Y
P
P
G
Y
N
P
E
G
K
A
V
Zebra Danio
Brachydanio rerio
NP_956198
409
46098
K335
K
D
E
V
D
E
I
K
K
F
D
D
P
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23976
631
72517
L539
Q
D
K
R
I
E
K
L
L
P
D
Y
E
M
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189673
580
65781
T505
T
D
D
M
V
D
H
T
E
P
N
K
E
M
I
Poplar Tree
Populus trichocarpa
XP_002317447
628
70376
S553
G
E
N
Y
D
E
E
S
D
M
G
S
G
K
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564012
621
70272
G546
Q
F
K
Q
S
I
Y
G
D
D
P
D
E
E
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SA95
645
72334
N555
E
M
L
A
K
K
A
N
D
L
Q
N
T
R
A
Conservation
Percent
Protein Identity:
100
88
89.8
84.7
N.A.
83.2
83.2
N.A.
53.6
68
65.6
39
N.A.
25
N.A.
N.A.
45.6
Protein Similarity:
100
89.3
91.1
92.9
N.A.
90.9
91.7
N.A.
59.9
81.9
81.1
53.2
N.A.
45.9
N.A.
N.A.
64.8
P-Site Identity:
100
100
100
80
N.A.
86.6
80
N.A.
0
73.3
80
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
13.3
86.6
80
13.3
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
30.7
N.A.
N.A.
30.2
N.A.
27.6
Protein Similarity:
50
N.A.
N.A.
48.6
N.A.
48.5
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
7
0
0
0
0
7
0
20
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
7
0
14
7
34
0
20
7
14
14
0
0
0
% D
% Glu:
54
7
7
0
0
20
7
0
14
0
54
0
20
7
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
7
% F
% Gly:
7
0
0
0
0
0
20
7
0
7
7
54
7
7
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
7
0
0
0
0
0
0
7
7
% I
% Lys:
7
0
14
0
7
7
7
7
7
0
7
7
54
14
0
% K
% Leu:
0
54
7
0
0
0
0
7
7
7
0
0
0
0
7
% L
% Met:
0
7
0
7
0
0
0
0
0
7
0
0
0
14
0
% M
% Asn:
0
0
7
0
7
0
7
7
40
0
7
7
0
0
0
% N
% Pro:
0
0
7
7
54
54
0
7
0
67
7
0
7
0
7
% P
% Gln:
20
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
7
% R
% Ser:
0
0
0
0
7
0
0
7
14
0
0
7
0
0
7
% S
% Thr:
7
0
0
0
0
0
0
7
0
0
0
0
7
0
20
% T
% Val:
7
0
54
7
7
0
0
0
0
0
0
0
7
27
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
60
0
7
7
54
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _