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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYL1
All Species:
20
Human Site:
S126
Identified Species:
40
UniProt:
P12980
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12980
NP_005574.2
280
29938
S126
G
P
F
S
I
F
P
S
S
R
L
K
R
R
P
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
G72
E
P
G
S
P
A
Q
G
K
R
G
K
K
S
A
Rhesus Macaque
Macaca mulatta
XP_001110523
737
77582
S410
G
P
F
S
V
F
P
S
S
R
L
K
R
R
P
Dog
Lupus familis
XP_853573
183
18958
R54
H
Q
S
S
S
P
P
R
L
P
P
G
V
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P27792
278
30123
N125
G
P
F
S
I
F
P
N
S
R
L
K
R
R
P
Rat
Rattus norvegicus
Q66HH3
278
29939
N125
G
P
F
S
I
F
P
N
S
R
L
K
R
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510416
353
37704
S149
G
P
F
S
I
F
Q
S
S
R
L
K
R
R
P
Chicken
Gallus gallus
P24899
311
33749
S156
D
S
F
S
M
Y
G
S
N
R
V
K
R
R
P
Frog
Xenopus laevis
O73823
394
43024
N239
T
F
P
M
Y
T
S
N
S
R
A
K
R
R
P
Zebra Danio
Brachydanio rerio
O93507
324
35687
S162
E
Q
Y
G
M
Y
P
S
N
R
V
K
R
R
P
Tiger Blowfish
Takifugu rubipres
Q90YI8
371
40876
S184
E
Q
Y
S
M
Y
P
S
N
R
V
K
R
R
P
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792477
400
43713
A125
L
S
P
T
I
I
A
A
P
Q
M
M
L
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.2
33.3
55.3
N.A.
77.8
80
N.A.
49.5
34.7
29.1
33.6
32.8
N.A.
N.A.
N.A.
27.2
Protein Similarity:
100
33.2
34.5
60
N.A.
83.5
84.2
N.A.
56.3
44
38.8
46.2
42.5
N.A.
N.A.
N.A.
39.7
P-Site Identity:
100
26.6
93.3
13.3
N.A.
93.3
93.3
N.A.
93.3
53.3
40
46.6
53.3
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
13.3
N.A.
100
100
N.A.
93.3
80
46.6
80
86.6
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
9
9
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
50
0
0
42
0
0
0
0
0
0
0
0
0
% F
% Gly:
42
0
9
9
0
0
9
9
0
0
9
9
0
9
9
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
42
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
84
9
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
9
0
42
0
9
0
0
% L
% Met:
0
0
0
9
25
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
25
25
0
0
0
0
0
0
% N
% Pro:
0
50
17
0
9
9
59
0
9
9
9
0
0
9
75
% P
% Gln:
0
25
0
0
0
0
17
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
84
0
0
75
75
0
% R
% Ser:
0
17
9
75
9
0
9
50
50
0
0
0
0
9
0
% S
% Thr:
9
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
25
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
9
25
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _