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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LYL1 All Species: 39.39
Human Site: S157 Identified Species: 78.79
UniProt: P12980 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12980 NP_005574.2 280 29938 S157 A R R V F T N S R E R W R Q Q
Chimpanzee Pan troglodytes Q8MI03 201 20743 G97 G G G G S S S G G G S P Q S Y
Rhesus Macaque Macaca mulatta XP_001110523 737 77582 S441 A R R V F T N S R E R W R Q Q
Dog Lupus familis XP_853573 183 18958 L79 A A V A T T E L S A L R P P L
Cat Felis silvestris
Mouse Mus musculus P27792 278 30123 S156 A R R V F T N S R E R W R Q Q
Rat Rattus norvegicus Q66HH3 278 29939 S156 A R R V F T N S R E R W R Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510416 353 37704 S180 A R R V F T N S R E R W R Q Q
Chicken Gallus gallus P24899 311 33749 S186 V R R I F T N S R E R W R Q Q
Frog Xenopus laevis O73823 394 43024 S269 V R R I F T N S R E R W R Q Q
Zebra Danio Brachydanio rerio O93507 324 35687 S192 V R R I F T N S R E R W R Q Q
Tiger Blowfish Takifugu rubipres Q90YI8 371 40876 S211 V R R I F T N S R E R W R Q Q
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792477 400 43713 S236 V R R I F T N S R E R W R Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.2 33.3 55.3 N.A. 77.8 80 N.A. 49.5 34.7 29.1 33.6 32.8 N.A. N.A. N.A. 27.2
Protein Similarity: 100 33.2 34.5 60 N.A. 83.5 84.2 N.A. 56.3 44 38.8 46.2 42.5 N.A. N.A. N.A. 39.7
P-Site Identity: 100 0 100 13.3 N.A. 100 100 N.A. 100 86.6 86.6 86.6 86.6 N.A. N.A. N.A. 86.6
P-Site Similarity: 100 20 100 13.3 N.A. 100 100 N.A. 100 93.3 93.3 93.3 93.3 N.A. N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 9 0 9 0 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 9 0 0 84 0 0 0 0 0 % E
% Phe: 0 0 0 0 84 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 9 9 0 0 0 9 9 9 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 42 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 84 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 9 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 9 84 84 % Q
% Arg: 0 84 84 0 0 0 0 0 84 0 84 9 84 0 0 % R
% Ser: 0 0 0 0 9 9 9 84 9 0 9 0 0 9 0 % S
% Thr: 0 0 0 0 9 92 0 0 0 0 0 0 0 0 0 % T
% Val: 42 0 9 42 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 84 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _