Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LYL1 All Species: 6.36
Human Site: T218 Identified Species: 12.73
UniProt: P12980 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P12980 NP_005574.2 280 29938 T218 A A L A A G P T P P G P R K R
Chimpanzee Pan troglodytes Q8MI03 201 20743 K146 L P S D K L S K I Q T L K L A
Rhesus Macaque Macaca mulatta XP_001110523 737 77582 G537 G S P S Q G R G T D A C R R R
Dog Lupus familis XP_853573 183 18958 L128 G I F P S S R L K R R P S H C
Cat Felis silvestris
Mouse Mus musculus P27792 278 30123 S217 A V L T S G P S A P G S R K P
Rat Rattus norvegicus Q66HH3 278 29939 S217 A V L A S G P S A P G S R K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510416 353 37704 P254 S P P L P G P P H A G G S E D
Chicken Gallus gallus P24899 311 33749 K250 N Q R G K V N K D S G I V Q E
Frog Xenopus laevis O73823 394 43024 K333 N Q R N K G N K D N G M V Q Q
Zebra Danio Brachydanio rerio O93507 324 35687 A252 D D M V G G E A P A R A N R D
Tiger Blowfish Takifugu rubipres Q90YI8 371 40876 H284 T G L M V G A H E V G P Q G G
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792477 400 43713 E304 E A V A A P M E I Y E N I E P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.2 33.3 55.3 N.A. 77.8 80 N.A. 49.5 34.7 29.1 33.6 32.8 N.A. N.A. N.A. 27.2
Protein Similarity: 100 33.2 34.5 60 N.A. 83.5 84.2 N.A. 56.3 44 38.8 46.2 42.5 N.A. N.A. N.A. 39.7
P-Site Identity: 100 0 20 6.6 N.A. 53.3 60 N.A. 20 6.6 13.3 13.3 26.6 N.A. N.A. N.A. 20
P-Site Similarity: 100 6.6 40 13.3 N.A. 66.6 73.3 N.A. 33.3 13.3 26.6 26.6 33.3 N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 17 0 25 17 0 9 9 17 17 9 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % C
% Asp: 9 9 0 9 0 0 0 0 17 9 0 0 0 0 17 % D
% Glu: 9 0 0 0 0 0 9 9 9 0 9 0 0 17 9 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 9 0 9 9 67 0 9 0 0 59 9 0 9 9 % G
% His: 0 0 0 0 0 0 0 9 9 0 0 0 0 9 0 % H
% Ile: 0 9 0 0 0 0 0 0 17 0 0 9 9 0 0 % I
% Lys: 0 0 0 0 25 0 0 25 9 0 0 0 9 25 0 % K
% Leu: 9 0 34 9 0 9 0 9 0 0 0 9 0 9 0 % L
% Met: 0 0 9 9 0 0 9 0 0 0 0 9 0 0 0 % M
% Asn: 17 0 0 9 0 0 17 0 0 9 0 9 9 0 0 % N
% Pro: 0 17 17 9 9 9 34 9 17 25 0 25 0 0 25 % P
% Gln: 0 17 0 0 9 0 0 0 0 9 0 0 9 17 9 % Q
% Arg: 0 0 17 0 0 0 17 0 0 9 17 0 34 17 17 % R
% Ser: 9 9 9 9 25 9 9 17 0 9 0 17 17 0 0 % S
% Thr: 9 0 0 9 0 0 0 9 9 0 9 0 0 0 0 % T
% Val: 0 17 9 9 9 9 0 0 0 9 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _