KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC5
All Species:
9.09
Human Site:
S145
Identified Species:
15.38
UniProt:
P13010
Number Species:
13
Phosphosite Substitution
Charge Score:
0.62
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13010
NP_066964.1
732
82705
S145
L
S
S
R
F
S
K
S
Q
L
D
I
I
I
H
Chimpanzee
Pan troglodytes
XP_001151933
785
88962
S198
L
S
S
R
F
S
K
S
Q
L
D
I
I
I
H
Rhesus Macaque
Macaca mulatta
XP_001084586
845
95939
S255
L
S
S
R
F
S
K
S
Q
L
D
I
I
I
H
Dog
Lupus familis
XP_536061
1026
114438
D241
L
S
S
P
F
S
K
D
Q
L
D
V
I
I
H
Cat
Felis silvestris
Mouse
Mus musculus
P27641
732
83038
D145
L
S
S
P
F
S
Q
D
Q
L
D
V
I
I
C
Rat
Rattus norvegicus
NP_803154
732
83096
D145
L
S
S
P
F
S
Q
D
Q
L
D
I
I
I
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422072
768
87067
D183
L
S
S
P
V
S
E
D
Q
L
E
I
I
I
A
Frog
Xenopus laevis
NP_001081127
726
82246
D144
L
S
S
P
F
S
V
D
Q
L
E
V
I
I
A
Zebra Danio
Brachydanio rerio
XP_001918508
727
81908
D144
L
N
I
Q
T
S
E
D
Q
L
D
I
I
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788472
779
85897
E138
L
F
S
D
L
G
G
E
F
A
D
D
K
L
Q
Poplar Tree
Populus trichocarpa
XP_002320725
700
79238
G137
K
Y
Q
A
T
N
K
G
K
K
R
L
C
L
I
Maize
Zea mays
NP_001147945
681
76556
P136
Q
E
L
L
R
D
P
P
E
G
T
K
E
D
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564520
680
76670
P136
A
A
C
P
T
K
D
P
F
E
G
T
K
D
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX73
725
80957
D146
G
E
S
P
I
D
D
D
Q
S
E
E
V
A
N
Conservation
Percent
Protein Identity:
100
92.9
80.2
59.2
N.A.
78.4
78.2
N.A.
N.A.
63.5
62.4
56.9
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
93.1
82.5
65.3
N.A.
87.6
87
N.A.
N.A.
77.3
79.3
76
N.A.
N.A.
N.A.
N.A.
55.8
P-Site Identity:
100
100
100
80
N.A.
66.6
73.3
N.A.
N.A.
60
60
53.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
N.A.
73.3
73.3
73.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
24.4
25.4
N.A.
24.1
N.A.
21.9
Protein Similarity:
45.9
45.9
N.A.
46.9
N.A.
40.8
P-Site Identity:
6.6
0
N.A.
0
N.A.
13.3
P-Site Similarity:
33.3
6.6
N.A.
6.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
0
0
0
0
8
0
0
0
8
15
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
15
% C
% Asp:
0
0
0
8
0
15
15
50
0
0
58
8
0
15
8
% D
% Glu:
0
15
0
0
0
0
15
8
8
8
22
8
8
0
0
% E
% Phe:
0
8
0
0
50
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
8
8
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
0
43
65
65
8
% I
% Lys:
8
0
0
0
0
8
36
0
8
8
0
8
15
0
0
% K
% Leu:
72
0
8
8
8
0
0
0
0
65
0
8
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
50
0
0
8
15
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
0
0
15
0
72
0
0
0
0
0
22
% Q
% Arg:
0
0
0
22
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
58
72
0
0
65
0
22
0
8
0
0
0
0
0
% S
% Thr:
0
0
0
0
22
0
0
0
0
0
8
8
0
0
0
% T
% Val:
0
0
0
0
8
0
8
0
0
0
0
22
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _