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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC5
All Species:
41.82
Human Site:
S324
Identified Species:
70.77
UniProt:
P13010
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13010
NP_066964.1
732
82705
S324
G
S
D
I
V
P
F
S
K
V
D
E
E
Q
M
Chimpanzee
Pan troglodytes
XP_001151933
785
88962
S377
G
S
D
I
V
P
F
S
K
V
D
E
E
Q
M
Rhesus Macaque
Macaca mulatta
XP_001084586
845
95939
S437
G
S
D
I
V
P
F
S
K
V
D
E
E
Q
M
Dog
Lupus familis
XP_536061
1026
114438
S420
G
S
D
I
V
P
F
S
K
V
D
E
E
H
M
Cat
Felis silvestris
Mouse
Mus musculus
P27641
732
83038
S324
G
S
D
I
I
P
F
S
K
V
D
E
E
Q
M
Rat
Rattus norvegicus
NP_803154
732
83096
S324
G
S
D
I
I
P
F
S
K
V
D
E
E
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422072
768
87067
S361
G
S
D
I
V
P
F
S
K
E
D
E
E
Q
M
Frog
Xenopus laevis
NP_001081127
726
82246
S323
G
S
D
I
V
P
F
S
K
V
D
Q
E
Q
M
Zebra Danio
Brachydanio rerio
XP_001918508
727
81908
S321
G
S
D
I
V
P
F
S
K
V
D
E
E
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788472
779
85897
S315
G
N
D
I
I
P
I
S
E
E
D
K
K
N
M
Poplar Tree
Populus trichocarpa
XP_002320725
700
79238
S318
G
P
Q
V
V
P
I
S
S
A
E
W
D
A
V
Maize
Zea mays
NP_001147945
681
76556
P324
F
T
D
R
S
S
V
P
R
H
Q
F
M
K
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564520
680
76670
L317
K
T
D
K
G
M
K
L
L
G
F
T
E
A
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX73
725
80957
G332
G
R
T
V
V
P
F
G
K
S
E
E
D
Y
L
Conservation
Percent
Protein Identity:
100
92.9
80.2
59.2
N.A.
78.4
78.2
N.A.
N.A.
63.5
62.4
56.9
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
93.1
82.5
65.3
N.A.
87.6
87
N.A.
N.A.
77.3
79.3
76
N.A.
N.A.
N.A.
N.A.
55.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
100
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
93.3
100
100
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
24.4
25.4
N.A.
24.1
N.A.
21.9
Protein Similarity:
45.9
45.9
N.A.
46.9
N.A.
40.8
P-Site Identity:
26.6
6.6
N.A.
13.3
N.A.
40
P-Site Similarity:
53.3
26.6
N.A.
20
N.A.
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
86
0
0
0
0
0
0
0
72
0
15
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
8
15
15
65
72
0
0
% E
% Phe:
8
0
0
0
0
0
72
0
0
0
8
8
0
0
0
% F
% Gly:
86
0
0
0
8
0
0
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
72
22
0
15
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
8
0
72
0
0
8
8
8
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
72
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
86
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
8
8
0
58
0
% Q
% Arg:
0
8
0
8
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
65
0
0
8
8
0
79
8
8
0
0
0
0
8
% S
% Thr:
0
15
8
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
15
65
0
8
0
0
58
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _