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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC5
All Species:
32.73
Human Site:
S436
Identified Species:
55.38
UniProt:
P13010
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13010
NP_066964.1
732
82705
S436
D
L
R
Q
Y
M
F
S
S
L
K
N
S
K
K
Chimpanzee
Pan troglodytes
XP_001151933
785
88962
S489
D
L
R
Q
Y
M
F
S
S
L
K
N
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001084586
845
95939
S549
D
L
R
Q
Y
M
F
S
S
L
K
N
S
K
K
Dog
Lupus familis
XP_536061
1026
114438
S532
D
L
R
Q
Y
M
F
S
S
F
K
N
N
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P27641
732
83038
S436
D
L
R
Q
Y
M
F
S
S
L
K
N
N
K
K
Rat
Rattus norvegicus
NP_803154
732
83096
S436
D
L
R
Q
Y
M
F
S
S
L
K
N
N
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422072
768
87067
S473
D
V
R
Q
Y
M
F
S
S
L
K
N
N
K
K
Frog
Xenopus laevis
NP_001081127
726
82246
S435
D
I
R
Q
Y
L
F
S
S
L
K
N
N
K
K
Zebra Danio
Brachydanio rerio
XP_001918508
727
81908
P433
D
L
R
Q
F
T
F
P
M
L
E
N
N
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788472
779
85897
M427
D
L
R
M
Y
T
F
M
S
L
D
N
N
K
R
Poplar Tree
Populus trichocarpa
XP_002320725
700
79238
P432
D
V
R
E
F
Q
F
P
S
F
S
S
F
P
A
Maize
Zea mays
NP_001147945
681
76556
S419
S
F
S
S
L
P
S
S
S
Q
P
T
E
E
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564520
680
76670
P414
D
V
R
E
F
P
F
P
S
F
N
K
L
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX73
725
80957
P444
D
V
R
S
Y
Q
F
P
P
L
D
K
V
L
T
Conservation
Percent
Protein Identity:
100
92.9
80.2
59.2
N.A.
78.4
78.2
N.A.
N.A.
63.5
62.4
56.9
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
93.1
82.5
65.3
N.A.
87.6
87
N.A.
N.A.
77.3
79.3
76
N.A.
N.A.
N.A.
N.A.
55.8
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
60
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
100
100
80
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
24.4
25.4
N.A.
24.1
N.A.
21.9
Protein Similarity:
45.9
45.9
N.A.
46.9
N.A.
40.8
P-Site Identity:
26.6
13.3
N.A.
26.6
N.A.
33.3
P-Site Similarity:
53.3
26.6
N.A.
46.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
93
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% D
% Glu:
0
0
0
15
0
0
0
0
0
0
8
0
8
8
0
% E
% Phe:
0
8
0
0
22
0
93
0
0
22
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
58
15
0
72
65
% K
% Leu:
0
58
0
0
8
8
0
0
0
72
0
0
8
8
0
% L
% Met:
0
0
0
8
0
50
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
72
50
0
0
% N
% Pro:
0
0
0
0
0
15
0
29
8
0
8
0
0
15
0
% P
% Gln:
0
0
0
65
0
15
0
0
0
8
0
0
0
0
8
% Q
% Arg:
0
0
93
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
0
8
15
0
0
8
65
86
0
8
8
22
0
8
% S
% Thr:
0
0
0
0
0
15
0
0
0
0
0
8
0
0
8
% T
% Val:
0
29
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
72
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _