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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC5
All Species:
19.39
Human Site:
S579
Identified Species:
32.82
UniProt:
P13010
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13010
NP_066964.1
732
82705
S579
G
G
A
H
F
S
V
S
S
L
A
E
G
S
V
Chimpanzee
Pan troglodytes
XP_001151933
785
88962
S632
G
G
A
H
F
S
V
S
S
L
A
E
G
S
V
Rhesus Macaque
Macaca mulatta
XP_001084586
845
95939
S692
G
G
A
H
F
S
V
S
S
L
A
E
G
S
V
Dog
Lupus familis
XP_536061
1026
114438
S676
G
E
P
C
F
S
I
S
S
L
A
E
G
S
V
Cat
Felis silvestris
Mouse
Mus musculus
P27641
732
83038
S580
E
E
D
H
I
S
I
S
S
L
A
E
G
N
I
Rat
Rattus norvegicus
NP_803154
732
83096
S580
E
E
G
H
I
S
I
S
S
L
A
E
G
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422072
768
87067
M616
E
E
D
S
F
S
I
M
K
L
A
E
G
N
V
Frog
Xenopus laevis
NP_001081127
726
82246
L576
E
G
F
S
L
L
R
L
A
D
G
N
V
T
S
Zebra Danio
Brachydanio rerio
XP_001918508
727
81908
A574
E
E
T
E
F
N
L
A
E
I
T
E
G
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788472
779
85897
D570
D
D
E
V
N
G
G
D
L
S
M
A
G
M
A
Poplar Tree
Populus trichocarpa
XP_002320725
700
79238
L563
H
Q
D
T
T
N
A
L
V
V
K
P
V
K
V
Maize
Zea mays
NP_001147945
681
76556
K534
T
G
A
G
D
Q
A
K
S
V
E
D
R
V
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564520
680
76670
N539
S
G
S
D
D
E
D
N
R
M
I
T
Y
D
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX73
725
80957
K576
R
G
R
K
D
T
V
K
P
L
S
G
L
D
I
Conservation
Percent
Protein Identity:
100
92.9
80.2
59.2
N.A.
78.4
78.2
N.A.
N.A.
63.5
62.4
56.9
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
93.1
82.5
65.3
N.A.
87.6
87
N.A.
N.A.
77.3
79.3
76
N.A.
N.A.
N.A.
N.A.
55.8
P-Site Identity:
100
100
100
73.3
N.A.
53.3
60
N.A.
N.A.
46.6
6.6
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
73.3
73.3
N.A.
N.A.
60
20
60
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
24.4
25.4
N.A.
24.1
N.A.
21.9
Protein Similarity:
45.9
45.9
N.A.
46.9
N.A.
40.8
P-Site Identity:
6.6
20
N.A.
6.6
N.A.
20
P-Site Similarity:
20
40
N.A.
26.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
29
0
0
0
15
8
8
0
50
8
0
0
15
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
22
8
22
0
8
8
0
8
0
8
0
15
0
% D
% Glu:
36
36
8
8
0
8
0
0
8
0
8
58
0
0
0
% E
% Phe:
0
0
8
0
43
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
29
50
8
8
0
8
8
0
0
0
8
8
65
0
0
% G
% His:
8
0
0
36
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
29
0
0
8
8
0
0
0
22
% I
% Lys:
0
0
0
8
0
0
0
15
8
0
8
0
0
8
0
% K
% Leu:
0
0
0
0
8
8
8
15
8
58
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
8
8
0
0
8
0
% M
% Asn:
0
0
0
0
8
15
0
8
0
0
0
8
0
29
0
% N
% Pro:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
8
0
0
0
8
0
8
0
0
0
8
0
0
% R
% Ser:
8
0
8
15
0
50
0
43
50
8
8
0
0
29
8
% S
% Thr:
8
0
8
8
8
8
0
0
0
0
8
8
0
8
0
% T
% Val:
0
0
0
8
0
0
29
0
8
15
0
0
15
8
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _