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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XRCC5 All Species: 21.82
Human Site: S580 Identified Species: 36.92
UniProt: P13010 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13010 NP_066964.1 732 82705 S580 G A H F S V S S L A E G S V T
Chimpanzee Pan troglodytes XP_001151933 785 88962 S633 G A H F S V S S L A E G S V T
Rhesus Macaque Macaca mulatta XP_001084586 845 95939 S693 G A H F S V S S L A E G S V T
Dog Lupus familis XP_536061 1026 114438 S677 E P C F S I S S L A E G S V T
Cat Felis silvestris
Mouse Mus musculus P27641 732 83038 S581 E D H I S I S S L A E G N I T
Rat Rattus norvegicus NP_803154 732 83096 S581 E G H I S I S S L A E G N V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422072 768 87067 K617 E D S F S I M K L A E G N V T
Frog Xenopus laevis NP_001081127 726 82246 A577 G F S L L R L A D G N V T S V
Zebra Danio Brachydanio rerio XP_001918508 727 81908 E575 E T E F N L A E I T E G N I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788472 779 85897 L571 D E V N G G D L S M A G M A M
Poplar Tree Populus trichocarpa XP_002320725 700 79238 V564 Q D T T N A L V V K P V K V E
Maize Zea mays NP_001147945 681 76556 S535 G A G D Q A K S V E D R V L E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_564520 680 76670 R540 G S D D E D N R M I T Y D A K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RX73 725 80957 P577 G R K D T V K P L S G L D I D
Conservation
Percent
Protein Identity: 100 92.9 80.2 59.2 N.A. 78.4 78.2 N.A. N.A. 63.5 62.4 56.9 N.A. N.A. N.A. N.A. 38.1
Protein Similarity: 100 93.1 82.5 65.3 N.A. 87.6 87 N.A. N.A. 77.3 79.3 76 N.A. N.A. N.A. N.A. 55.8
P-Site Identity: 100 100 100 73.3 N.A. 60 66.6 N.A. N.A. 53.3 6.6 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 80 N.A. 80 80 N.A. N.A. 66.6 20 66.6 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: 24.4 25.4 N.A. 24.1 N.A. 21.9
Protein Similarity: 45.9 45.9 N.A. 46.9 N.A. 40.8
P-Site Identity: 6.6 20 N.A. 6.6 N.A. 20
P-Site Similarity: 20 40 N.A. 26.6 N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 29 0 0 0 15 8 8 0 50 8 0 0 15 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 22 8 22 0 8 8 0 8 0 8 0 15 0 8 % D
% Glu: 36 8 8 0 8 0 0 8 0 8 58 0 0 0 15 % E
% Phe: 0 8 0 43 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 8 8 0 8 8 0 0 0 8 8 65 0 0 0 % G
% His: 0 0 36 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 15 0 29 0 0 8 8 0 0 0 22 0 % I
% Lys: 0 0 8 0 0 0 15 8 0 8 0 0 8 0 8 % K
% Leu: 0 0 0 8 8 8 15 8 58 0 0 8 0 8 0 % L
% Met: 0 0 0 0 0 0 8 0 8 8 0 0 8 0 8 % M
% Asn: 0 0 0 8 15 0 8 0 0 0 8 0 29 0 0 % N
% Pro: 0 8 0 0 0 0 0 8 0 0 8 0 0 0 0 % P
% Gln: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 8 0 8 0 0 0 8 0 0 0 % R
% Ser: 0 8 15 0 50 0 43 50 8 8 0 0 29 8 0 % S
% Thr: 0 8 8 8 8 0 0 0 0 8 8 0 8 0 58 % T
% Val: 0 0 8 0 0 29 0 8 15 0 0 15 8 50 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _