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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC5
All Species:
38.48
Human Site:
Y397
Identified Species:
65.13
UniProt:
P13010
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13010
NP_066964.1
732
82705
Y397
V
A
I
V
R
Y
A
Y
D
K
R
A
N
P
Q
Chimpanzee
Pan troglodytes
XP_001151933
785
88962
Y450
V
A
I
V
R
Y
A
Y
D
K
R
A
N
P
Q
Rhesus Macaque
Macaca mulatta
XP_001084586
845
95939
Y510
V
A
I
V
R
Y
A
Y
D
K
R
A
N
P
Q
Dog
Lupus familis
XP_536061
1026
114438
Y493
V
A
V
V
R
Y
A
Y
D
R
R
S
H
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
P27641
732
83038
Y397
V
A
I
V
R
Y
A
Y
D
K
R
S
N
P
Q
Rat
Rattus norvegicus
NP_803154
732
83096
Y397
V
A
I
V
R
Y
A
Y
D
K
R
A
N
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422072
768
87067
Y434
V
A
I
V
R
Y
A
Y
D
R
R
C
N
P
Q
Frog
Xenopus laevis
NP_001081127
726
82246
Y396
V
A
I
V
R
Y
V
Y
D
R
R
S
N
P
Q
Zebra Danio
Brachydanio rerio
XP_001918508
727
81908
Y394
A
A
I
V
R
Y
A
Y
D
R
R
S
N
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788472
779
85897
Y388
V
A
I
V
R
R
A
Y
S
G
S
S
A
P
R
Poplar Tree
Populus trichocarpa
XP_002320725
700
79238
W389
V
A
I
L
R
C
V
W
R
Q
G
Q
G
S
V
Maize
Zea mays
NP_001147945
681
76556
P382
V
A
I
G
V
L
T
P
N
I
S
S
V
N
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564520
680
76670
V379
R
N
G
Q
G
N
V
V
V
G
V
L
T
P
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RX73
725
80957
N403
Y
A
V
A
R
Y
V
N
K
D
K
A
P
P
Q
Conservation
Percent
Protein Identity:
100
92.9
80.2
59.2
N.A.
78.4
78.2
N.A.
N.A.
63.5
62.4
56.9
N.A.
N.A.
N.A.
N.A.
38.1
Protein Similarity:
100
93.1
82.5
65.3
N.A.
87.6
87
N.A.
N.A.
77.3
79.3
76
N.A.
N.A.
N.A.
N.A.
55.8
P-Site Identity:
100
100
100
73.3
N.A.
93.3
100
N.A.
N.A.
86.6
80
80
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
24.4
25.4
N.A.
24.1
N.A.
21.9
Protein Similarity:
45.9
45.9
N.A.
46.9
N.A.
40.8
P-Site Identity:
26.6
20
N.A.
6.6
N.A.
40
P-Site Similarity:
46.6
33.3
N.A.
6.6
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
93
0
8
0
0
65
0
0
0
0
36
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
65
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
0
0
0
15
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
79
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
36
8
0
0
0
0
% K
% Leu:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
8
8
0
0
0
58
8
8
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
8
86
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
72
% Q
% Arg:
8
0
0
0
86
8
0
0
8
29
65
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
15
43
0
8
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% T
% Val:
79
0
15
72
8
0
29
8
8
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
72
0
72
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _