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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR2C1 All Species: 10.3
Human Site: S382 Identified Species: 18.89
UniProt: P13056 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13056 NP_001027458.1 603 67315 S382 A F R L T M P S P M P E Y L N
Chimpanzee Pan troglodytes XP_001137621 678 75113 S457 A F R L T M P S P M P E Y L N
Rhesus Macaque Macaca mulatta XP_001107297 554 61731 A339 L N P G E S T A C Q S S V A G
Dog Lupus familis XP_854792 605 67422 P383 V A F R L T M P S P M P E Y L
Cat Felis silvestris
Mouse Mus musculus Q505F1 590 65487 Y374 M P S P M P E Y L N V H Y I G
Rat Rattus norvegicus Q8VIJ4 590 65509 Y374 M P S P M P E Y L N V H Y I G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510105 561 61971 L346 P S P M P E Y L N V H Y I C E
Chicken Gallus gallus O42101 501 57084 L286 Q A K I M A Y L Q Q E Q A N R
Frog Xenopus laevis Q66J63 637 70793 S416 A F R L T M P S P M P E Y L N
Zebra Danio Brachydanio rerio Q06725 411 45463 Q196 P T S R Y G S Q C M Q P N N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16375 543 57969 Q328 Y P T S R Y G Q C M Q P N N I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9N4B8 615 68010 R375 V H F V K D S R V S L R T S T
Sea Urchin Strong. purpuratus Q26622 583 63834 C367 F L N V H Y I C E S A S R L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 90.3 96 N.A. 87.5 87.5 N.A. 77.7 21.5 72.6 27 N.A. 22 N.A. 22.9 49
Protein Similarity: 100 87.6 91.2 97.6 N.A. 92.2 91.7 N.A. 84.7 40.9 82.7 42.7 N.A. 37.8 N.A. 42.1 65.1
P-Site Identity: 100 100 0 0 N.A. 6.6 6.6 N.A. 0 0 100 6.6 N.A. 6.6 N.A. 0 6.6
P-Site Similarity: 100 100 6.6 0 N.A. 13.3 13.3 N.A. 13.3 20 100 6.6 N.A. 6.6 N.A. 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 16 0 0 0 8 0 8 0 0 8 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 8 24 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 8 16 0 8 0 8 24 8 0 8 % E
% Phe: 8 24 16 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 8 8 0 0 0 0 0 0 0 24 % G
% His: 0 8 0 0 8 0 0 0 0 0 8 16 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 0 0 0 8 16 16 % I
% Lys: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 0 24 8 0 0 16 16 0 8 0 0 31 16 % L
% Met: 16 0 0 8 24 24 8 0 0 39 8 0 0 0 0 % M
% Asn: 0 8 8 0 0 0 0 0 8 16 0 0 16 24 24 % N
% Pro: 16 24 16 16 8 16 24 8 24 8 24 24 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 16 8 16 16 8 0 0 0 % Q
% Arg: 0 0 24 16 8 0 0 8 0 0 0 8 8 0 8 % R
% Ser: 0 8 24 8 0 8 16 24 8 16 8 16 0 8 0 % S
% Thr: 0 8 8 0 24 8 8 0 0 0 0 0 8 0 8 % T
% Val: 16 0 0 16 0 0 0 0 8 8 16 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 16 16 16 0 0 0 8 39 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _